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局部应用芦荟促进皮肤烧伤创面愈合的作用:1例病例报告。

Role of topical application of Aloe Vera for accelerated wound healing of cutaneous burns Wound: A case report.

作者信息

Reddy K SriHarsha, Chittoria Ravi Kumar, Kerakada Nishad, Thomas Neljo, Srinath R, Indushekar T C, Sriram V S

机构信息

Department of Plastic Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.

Department of Plastic Surgery and Telemedicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.

出版信息

J Cutan Aesthet Surg. 2024 Jul-Sep;17(3):246-248. doi: 10.4103/JCAS.JCAS_8_22. Epub 2022 Dec 2.

DOI:10.4103/JCAS.JCAS_8_22
PMID:39483652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11497533/
Abstract

Aloe vera is a cactus plant that thrives in warm areas. Since ancient times, it has been used to treat acute wounds. However, the efficacy of aloe vera for burns and split-thickness skin graft (STSG) donor sites is inconclusive. In this study, we have applied pure aloe vera gel extract as an adjunct to dressing second-degree (superficial) burn wounds and assessed the time for complete epithelialization. The time taken for complete epithelialization of the wound was 11 days when compared to the normal (evidence-based) time of 14 days.

摘要

芦荟是一种在温暖地区生长旺盛的仙人掌植物。自古以来,它就被用于治疗急性伤口。然而,芦荟对烧伤和中厚皮片(STSG)供皮区的疗效尚无定论。在本研究中,我们应用纯芦荟凝胶提取物辅助治疗二度(浅度)烧伤创面,并评估完全上皮化的时间。与正常(循证)的14天相比,创面完全上皮化所需时间为11天。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f6/11497533/d51237cf3993/JCAS-17-246-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f6/11497533/efcdcc5b8731/JCAS-17-246-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f6/11497533/d1ddbd6d128e/JCAS-17-246-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f6/11497533/d51237cf3993/JCAS-17-246-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f6/11497533/efcdcc5b8731/JCAS-17-246-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f6/11497533/d1ddbd6d128e/JCAS-17-246-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48f6/11497533/d51237cf3993/JCAS-17-246-g003.jpg

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Role of topical application of Aloe Vera for accelerated wound healing of cutaneous burns Wound: A case report.局部应用芦荟促进皮肤烧伤创面愈合的作用:1例病例报告。
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本文引用的文献

1
Topical Aloe Vera Gel for Accelerated Wound Healing of Split-Thickness Skin Graft Donor Sites: A Double-Blind, Randomized, Controlled Trial and Systematic Review.局部应用库拉索芦荟凝胶加速切取中厚皮片供皮区创面愈合:一项双盲、随机、对照临床试验及系统评价。
Plast Reconstr Surg. 2018 Jul;142(1):217-226. doi: 10.1097/PRS.0000000000004515.
2
Topical Application of Aloe vera Accelerated Wound Healing, Modeling, and Remodeling: An Experimental Study.芦荟局部应用促进伤口愈合、塑形和重塑:一项实验研究。
Ann Plast Surg. 2016 Jan;77(1):37-46. doi: 10.1097/SAP.0000000000000239.
3
In vitro anti inflammatory activity of Aloe vera by down regulation of MMP-9 in peripheral blood mononuclear cells.
通过下调外周血单个核细胞中 MMP-9 表达水平评价库拉索芦荟的体外抗炎活性。
J Ethnopharmacol. 2012 May 7;141(1):542-6. doi: 10.1016/j.jep.2012.02.040. Epub 2012 Mar 15.
4
Preliminary evaluation: the effects of Aloe ferox Miller and Aloe arborescens Miller on wound healing.初步评估:费氏芦荟和木立芦荟对伤口愈合的影响。
J Ethnopharmacol. 2008 Nov 20;120(2):181-9. doi: 10.1016/j.jep.2008.08.008. Epub 2008 Aug 15.
5
The efficacy of aloe vera used for burn wound healing: a systematic review.芦荟用于烧伤创面愈合的疗效:一项系统评价。
Burns. 2007 Sep;33(6):713-8. doi: 10.1016/j.burns.2006.10.384. Epub 2007 May 17.
6
Chemical characterization of the immunomodulating polysaccharide of Aloe vera L.库拉索芦荟免疫调节多糖的化学特性
Carbohydr Res. 2005 May 2;340(6):1131-42. doi: 10.1016/j.carres.2005.02.016.
7
Identification of optimal molecular size of modified Aloe polysaccharides with maximum immunomodulatory activity.鉴定具有最大免疫调节活性的改性芦荟多糖的最佳分子大小。
Int Immunopharmacol. 2005 Feb;5(2):271-9. doi: 10.1016/j.intimp.2004.09.031.
8
Influence of Aloe vera on collagen turnover in healing of dermal wounds in rats.芦荟对大鼠皮肤伤口愈合中胶原蛋白更新的影响。
Indian J Exp Biol. 1998 Sep;36(9):896-901.
9
Activation of a mouse macrophage cell line by acemannan: the major carbohydrate fraction from Aloe vera gel.乙酰化甘露聚糖对小鼠巨噬细胞系的激活作用:库拉索芦荟凝胶中的主要碳水化合物成分。
Immunopharmacology. 1996 Nov;35(2):119-28. doi: 10.1016/s0162-3109(96)00135-x.
10
Aloe vera dermal wound gel is associated with a delay in wound healing.芦荟真皮伤口凝胶会导致伤口愈合延迟。
Obstet Gynecol. 1991 Jul;78(1):115-7.