Yang Yongxiang, Zhu Xiansong, Yang Tao, Fan Kexia, Cheng Jingmin, Ma Yuan
Department of Neurosurgery, The General Hospital of Western Theater Command, Chengdu, China.
Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, China.
Front Neurol. 2024 Oct 17;15:1453629. doi: 10.3389/fneur.2024.1453629. eCollection 2024.
Chronic subdural hematoma (CSDH) is a common neurologic disorder with increasing incidence, which can be preceded by head trauma or occur in the absence of trauma. In order to deeply understand the clinical characteristics of this disease, we conducted this retrospective study to explore the clinical differences between traumatic and not otherwise specified (NOS) CSDH.
According to the inclusion and exclusion criteria, 168 traumatic CSDH patients and 133 NOS CSDH patients were recruited from January 2015 to October 2023 in our cohort. The collected data and compared parameters including baseline clinical features and radiological outcomes of hematoma within 24 h of hospital admission, as well as the treatment method and clinical outcome of traumatic and NOS CSDH patients.
Compared to NOS CSDH patients, the average age was younger, epilepsy was more frequent, asymptomatic cases were more common, and the taking of anticoagulants and antiplatelet drugs were rarer in traumatic CSDH patients (all < 0.05). However, no differences were found in the radiological presentations of hematoma at admission, the treatment methods and clinical outcomes of traumatic and NOS CSDH patients (all > 0.05).
Traumatic CSDH patients were more likely to be asymptomatic or have seizures, while NOS CSDH were more common in elder people and in individuals with the history of taking anticoagulants and antiplatelet drugs. The treatment methods and clinical outcomes were similar in traumatic and NOS CSDH patients.
慢性硬膜下血肿（CSDH）是一种发病率不断上升的常见神经系统疾病，可由头部外伤引发，也可在无外伤的情况下发生。为深入了解该疾病的临床特征，我们开展了这项回顾性研究，以探讨创伤性与非创伤性（未另作说明，NOS）CSDH之间的临床差异。
根据纳入和排除标准，我们的队列研究在2015年1月至2023年10月期间招募了168例创伤性CSDH患者和133例NOS CSDH患者。收集的数据并比较的参数包括入院24小时内的基线临床特征和血肿的影像学结果，以及创伤性和NOS CSDH患者的治疗方法和临床结局。
与NOS CSDH患者相比，创伤性CSDH患者的平均年龄更小，癫痫发作更频繁，无症状病例更常见，服用抗凝药和抗血小板药物的情况更少见（均P<0.05）。然而，入院时血肿的影像学表现、创伤性和NOS CSDH患者的治疗方法及临床结局均无差异（均P>0.05）。
创伤性CSDH患者更易无症状或发生癫痫发作，而NOS CSDH在老年人以及有服用抗凝药和抗血小板药物史的个体中更为常见。创伤性和NOS CSDH患者的治疗方法及临床结局相似。
