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澳大利亚儿童中期至青少年中期疾病的起源与发展路径：早期不良状况及其长期影响。

Origins and developmental paths of medical conditions from mid-childhood to mid-adolescence in Australia: Early-life adverse conditions and their lasting effects.

作者信息

Nguyen Lan, Connelly Luke B, Birch Stephen, Nguyen Ha Trong

机构信息

Centre for the Business and Economics of Health, The University of Queensland, Brisbane, Australia.

Department of Sociology and Business Law, The University of Bologna, Bologna, Italy.

出版信息

SSM Popul Health. 2024 Oct 10;28:101717. doi: 10.1016/j.ssmph.2024.101717. eCollection 2024 Dec.

DOI:10.1016/j.ssmph.2024.101717
PMID:39484631
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11525227/
Abstract

This study investigates various common medical conditions affecting Australian children aged 4-14 years and the impact of prenatal and early-life conditions on these health conditions using a large national data set (n = 4122) with 15 years of follow-up. Consistent with the developmental origins of health and diseases hypothesis and the life-course models of health, the environment and parental financial hardship during pregnancy and shortly after birth play a significant role and have a lasting impact on the medical conditions of children. These significant effects are not reduced by controlling for child, family, and neighbourhood characteristics. The impact of improvements in family income when the child is aged 4-14 years does not compensate for the impact of health disadvantages in the prenatal and postnatal period.

摘要

本研究利用一个包含4122个样本且有15年随访期的大型全国数据集，调查了影响澳大利亚4至14岁儿童的各种常见病症，以及产前和生命早期状况对这些健康状况的影响。与健康和疾病的发育起源假说以及健康的生命历程模型一致，孕期和出生后不久的环境及父母经济困难发挥了重要作用，并对儿童的健康状况产生了持久影响。通过控制儿童、家庭和邻里特征，这些显著影响并未减弱。孩子4至14岁时家庭收入改善所产生的影响，并不能弥补产前和产后健康劣势所带来的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e60f/11525227/fc25725718c6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e60f/11525227/2aab2e7c2f27/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e60f/11525227/fc25725718c6/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e60f/11525227/2aab2e7c2f27/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e60f/11525227/fc25725718c6/gr2.jpg

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本文引用的文献

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Asthma and anxiety development in Australian children and adolescents.澳大利亚儿童和青少年哮喘和焦虑症的发展。
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SSM Popul Health. 2022 Mar 8;17:101061. doi: 10.1016/j.ssmph.2022.101061. eCollection 2022 Mar.
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Child health as human capital.儿童健康是人力资本。
Health Econ. 2020 Apr;29(4):452-463. doi: 10.1002/hec.3995. Epub 2020 Jan 21.
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Managing asthma in pregnancy: effects on future child health.孕期哮喘管理：对未来儿童健康的影响。
Lancet Respir Med. 2019 Jun;7(6):485-486. doi: 10.1016/S2213-2600(19)30149-3.
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Impact of birthweight on health-care utilization during early childhood - a birth cohort study.出生体重对儿童早期医疗保健利用的影响——一项出生队列研究。
BMC Pediatr. 2019 Mar 1;19(1):69. doi: 10.1186/s12887-019-1424-8.