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Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial.斯巴森坦治疗 IgA 肾病患者：一项随机、双盲、活性对照临床试验的预先指定中期分析。
Lancet. 2023 May 13;401(10388):1584-1594. doi: 10.1016/S0140-6736(23)00569-X. Epub 2023 Apr 1.
2
Inaxaplin for Proteinuric Kidney Disease in Persons with Two Variants.Inaxaplin 用于伴有两种变异的蛋白尿性肾病患者。
N Engl J Med. 2023 Mar 16;388(11):969-979. doi: 10.1056/NEJMoa2202396.
3
FDA approval of dapagliflozin for chronic kidney disease: a remarkable achievement?达格列净获美国食品药品监督管理局批准用于慢性肾病：一项非凡成就？
Lancet. 2021 Jul 24;398(10297):283-284. doi: 10.1016/S0140-6736(21)01242-3. Epub 2021 Jun 4.
4
GLP-1 Receptor Agonists in Diabetic Kidney Disease.糖尿病肾病中的胰高血糖素样肽-1受体激动剂
Clin J Am Soc Nephrol. 2021 Oct;16(10):1578-1580. doi: 10.2215/CJN.18771220. Epub 2021 Apr 13.
5
Proteinuria Reduction as a Surrogate End Point in Trials of IgA Nephropathy.蛋白尿减少作为 IgA 肾病试验的替代终点。
Clin J Am Soc Nephrol. 2019 Mar 7;14(3):469-481. doi: 10.2215/CJN.08600718. Epub 2019 Jan 11.
6
Risk Alleles are Associated with More Severe Arteriosclerosis in Renal Resistance Vessels with Aging and Hypertension.风险等位基因与衰老和高血压导致的肾阻力血管中更严重的动脉硬化有关。
Kidney Int Rep. 2016 May;1(1):10-23. doi: 10.1016/j.ekir.2016.03.002. Epub 2016 Apr 20.
7
Exploring the genetic basis of early-onset chronic kidney disease.探索早发性慢性肾脏病的遗传基础。
Nat Rev Nephrol. 2016 Mar;12(3):133-46. doi: 10.1038/nrneph.2015.205. Epub 2016 Jan 11.
8
Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models.肌动蛋白依赖性发动蛋白寡聚化的药理学靶向改善了多种动物模型中的慢性肾病。
Nat Med. 2015 Jun;21(6):601-9. doi: 10.1038/nm.3843. Epub 2015 May 11.
9
APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy.APOL1 基因变异与局灶节段性肾小球硬化和 HIV 相关性肾病。
J Am Soc Nephrol. 2011 Nov;22(11):2129-37. doi: 10.1681/ASN.2011040388. Epub 2011 Oct 13.
10
Modification of kidney barrier function by the urokinase receptor.尿激酶受体对肾脏屏障功能的调节
Nat Med. 2008 Jan;14(1):55-63. doi: 10.1038/nm1696. Epub 2007 Dec 16.

Treatment of Podocytopathies: Risky Business and Our Personal Journey.

作者信息

Sever Sanja, Reiser Jochen

机构信息

Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts.

The University of Texas Medical Branch at Galveston, Galveston, Texas.

出版信息

J Am Soc Nephrol. 2024 Nov 1;35(11):1600-1602. doi: 10.1681/ASN.0000000000000415. Epub 2024 May 15.

DOI:10.1681/ASN.0000000000000415
PMID:39484859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11543009/
Abstract
摘要