Department of Urology, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu Medical College, Chengdu, People's Republic of China.
Department of Gynecology, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu Medical College, Chengdu, People's Republic of China.
PLoS One. 2024 Nov 1;19(11):e0312869. doi: 10.1371/journal.pone.0312869. eCollection 2024.
Obstructive sleep apnea (OSA) and urinary incontinence (UI) are two prevalent health conditions with significant impacts on individuals' quality of life. Although they appear distinct in nature, a growing body of evidence suggests a potential interrelationship between these conditions. Our objective was to explore the association between the risk of OSA and the occurrence of UI within a nationally representative sample of U.S. adults. Utilizing cross-sectional data from the National Health and Nutrition Examination Survey spanning the years 2015 to 2020, we conducted an analysis on a sample comprising 8,647 adults who provided comprehensive self-reported information on both UI and sleep apnea symptoms. The included cohorts were analyzed based on their sex. We employed the Multivariate Apnea Prediction (MAP) index to evaluate the risk of OSA. Subgroup analyses were conducted, categorizing them according to different types of UI. The association between OSA risk and UI was estimated through multivariable binary logistic regression models. After adjusting for relevant confounders, our results revealed a positive correlation between OSA risk and UI in both males (OR = 5.68, 95% CI = 1.74-18.47) and females (OR = 5.99, 95% CI = 2.68-13.41). The subgroup analysis illustrates that an elevated risk of OSA heightens the likelihood of experiencing stress urinary incontinence (SUI), urge urinary incontinence (UUI), and mixed urinary incontinence (MUI) in both male and female populations. Our study findings imply that an elevated risk of OSA exacerbates the likelihood of UI, SUI, UUI and MUI.
阻塞性睡眠呼吸暂停(OSA)和尿失禁(UI)是两种普遍存在的健康问题,对个人的生活质量有重大影响。尽管它们在性质上似乎截然不同,但越来越多的证据表明这两种情况之间可能存在关联。我们的目的是探讨美国成年人全国代表性样本中 OSA 风险与 UI 发生之间的关联。我们利用 2015 年至 2020 年国家健康和营养检查调查的横断面数据,对一个包含 8647 名成年人的样本进行了分析,这些成年人提供了关于 UI 和睡眠呼吸暂停症状的全面自我报告信息。根据他们的性别对纳入的队列进行了分析。我们使用多变量呼吸暂停预测(MAP)指数评估 OSA 风险。进行了亚组分析,根据不同类型的 UI 对其进行分类。通过多变量二项逻辑回归模型估计 OSA 风险与 UI 之间的关联。在调整了相关混杂因素后,我们的结果表明 OSA 风险与 UI 之间存在正相关,无论男性(OR=5.68,95%CI=1.74-18.47)还是女性(OR=5.99,95%CI=2.68-13.41)。亚组分析表明,OSA 风险升高会增加男性和女性发生压力性尿失禁(SUI)、急迫性尿失禁(UUI)和混合性尿失禁(MUI)的可能性。我们的研究结果表明,OSA 风险升高会加剧 UI、SUI、UUI 和 MUI 的可能性。