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运动强度和持续时间对女性轻度高血压患者游泳训练引起的心脏结构和功能适应性的影响。

The impact of exercise intensity and duration for swim training-induced adaptations in cardiac structure and function in women with mild hypertension.

机构信息

Faculty of Health Sciences, Centre of Health Science, University of the Faroe Islands, Tórshavn, Faroe Islands, Denmark.

Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.

出版信息

Physiol Rep. 2024 Nov;12(21):e70116. doi: 10.14814/phy2.70116.

Abstract

This study aimed to investigate the impact of swim training intensity and duration on cardiac structure and function in mildly hypertensive women. Sixty-two mildly hypertensive women were randomized to 15 weeks of either (1) high-intensity swimming (HIS, n = 21), (2) moderate-intensity swimming (MOD, n = 21) or (3) control (CON, n = 20). Training sessions occurred three times per week. Cardiac measurements were conducted using echocardiography pre- and post-intervention. Both the HIS and MOD groups demonstrated significant within-group increases in left ventricular mass: 7.3% [1.2; 13.2] (p = 0.02) for HIS and 6.2% [0.5; 11.8] (p = 0.03) for MOD. The MOD group also demonstrated a significant increase in left ventricular internal dimension at end-diastole by 2.4% [0.2; 4.6] (p = 0.03). Post-hoc analysis of diastolic function markers revealed reduced mitral valve A velocity in both HIS (-14% [-25; -3], p = 0.02) and MOD (-13% [-23; -3], p = 0.01), leading to increased mitral valve E/A ratios of 27% [10; 47] (p = 0.003) and 22% [5; 40] (p = 0.01), respectively. Additionally, only MOD demonstrated increased left atrial diameter of 4.9% [0.7; 9.1] (p =0.02). A significant time×group effect (p = 0.02) existed for global longitudinal strain, which increased by 1.6% [0.2; 3.0] (p = 0.03) in MOD only. In conclusion, swim training for 15 weeks increased left ventricular mass and improved markers of diastolic function in mildly hypertensive women. These independent of exercise intensity and duration in mildly hypertensive women.

摘要

本研究旨在探讨游泳训练强度和时间对轻度高血压女性心脏结构和功能的影响。62 名轻度高血压女性随机分为 15 周的高强度游泳组(HIS,n=21)、中强度游泳组(MOD,n=21)或对照组(CON,n=20)。每周训练 3 次。干预前后使用超声心动图进行心脏测量。HIS 和 MOD 组的左心室质量均有显著的组内增加:7.3% [1.2; 13.2](p=0.02)和 6.2% [0.5; 11.8](p=0.03)。MOD 组还显示左心室舒张末期内径增加了 2.4% [0.2; 4.6](p=0.03)。舒张功能标志物的事后分析显示,HIS 组(-14% [-25; -3],p=0.02)和 MOD 组(-13% [-23; -3],p=0.01)的二尖瓣 A 速度均降低,导致二尖瓣 E/A 比值分别增加 27% [10; 47](p=0.003)和 22% [5; 40](p=0.01)。此外,只有 MOD 组显示左心房直径增加了 4.9% [0.7; 9.1](p=0.02)。整体纵向应变存在时间×组的显著效应(p=0.02),仅在 MOD 组增加了 1.6% [0.2; 3.0](p=0.03)。总之,15 周的游泳训练增加了轻度高血压女性的左心室质量,并改善了舒张功能标志物。这些改变与轻度高血压女性的运动强度和时间无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea4e/11530408/6c21d45a3abe/PHY2-12-e70116-g002.jpg

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