College of Traditional Chinese Medicine and Food Engineering, Shanxi University of Chinese Medicine, Taiyuan, China.
School of Medicine, Jiangsu University, Zhenjiang, China.
Carbohydr Res. 2024 Nov;545:109298. doi: 10.1016/j.carres.2024.109298. Epub 2024 Oct 23.
Portulaca oleracea L., a plant with both edible and medicinal properties, is traditionally valued for its diuretic, antipyretic, antiseptic, antispasmodic, and anthelmintic functions in folk medicine. P. oleracea polysaccharide (POP), a pivotal bioactive component, has various biological activities. Notably, their immunomodulatory capabilities have emerged as a significant area of research. The extraction, purification, monosaccharide composition, structure characterization, and biological activity of POP have been extensively investigated to identify the active components and to clarify their pharmacological actions and underlying molecular mechanisms. It aims to delineate the pharmacological mechanisms and molecular pathways associated with these polysaccharides, thereby underscoring their therapeutic promise and nutritional significance. Furthermore, the review critically examines the current research landscape of POP, identifying gaps and proposing innovative perspectives to enrich the scientific discourse surrounding these bioactive compounds.
马齿苋（Portulaca oleracea L.）是一种兼具食用和药用价值的植物，在民间医学中，因其具有利尿、解热、防腐、抗痉挛和驱虫的功能而受到重视。马齿苋多糖（POP）作为一种重要的生物活性成分，具有多种生物活性。值得注意的是，其免疫调节能力已成为一个重要的研究领域。人们对 POP 的提取、纯化、单糖组成、结构特征和生物活性进行了广泛的研究，以确定其活性成分，并阐明其药理作用和潜在的分子机制。旨在描绘这些多糖相关的药理学机制和分子途径，从而强调其治疗潜力和营养意义。此外，该综述还批判性地审视了目前关于 POP 的研究现状，确定了研究空白，并提出了创新观点，以丰富围绕这些生物活性化合物的科学讨论。
