Borella P, Picco P, Masellis G
Int Arch Occup Environ Health. 1986;57(2):93-9. doi: 10.1007/BF00381376.
Lead concentration was determined in abortion material obtained from non-professionally exposed women following legal abortions. Furthermore, lead and free erythrocyte porphyrin levels in mother's blood were measured. Under conditions of apparent "normal" lead exposure, we detected lead levels in abortion products which were between 0.07 and 5.29 micrograms/g dry weight with a geometric mean of 1.27. No significant correlation was observed between the parameters measured in mother's blood and lead content in the specimens of the first trimester. The influence of different factors, such as smoking, area of residence, gestational age and parity, was also investigated. None of these factors showed a contributory effect on the total variation of lead in abortion material. From these data, we can conclude that, at least in our population, lead does not accumulate in human embryos/fetuses in the first trimester of pregnancy.
测定了从合法堕胎的非职业暴露女性获得的流产物质中的铅浓度。此外,还测量了母亲血液中的铅和游离红细胞卟啉水平。在明显“正常”铅暴露的情况下,我们检测到流产产物中的铅水平在0.07至5.29微克/克干重之间,几何平均值为1.27。在母亲血液中测量的参数与孕早期标本中的铅含量之间未观察到显著相关性。还研究了不同因素的影响,如吸烟、居住地区、孕周和产次。这些因素均未对流产物质中铅的总变化产生影响。从这些数据中,我们可以得出结论,至少在我们的人群中,铅在妊娠早期不会在人类胚胎/胎儿中蓄积。