两名哮喘患者体内针对哌嗪和N-甲基哌嗪的IgE抗体

IgE antibodies against piperazine and N-methyl-piperazine in two asthmatic subjects.

作者信息

Welinder H, Hagmar L, Gustavsson C

出版信息

Int Arch Allergy Appl Immunol. 1986;79(3):259-62. doi: 10.1159/000233983.

Abstract

The presence of specific IgE antibodies against conjugates between human serum albumin and piperazine, a compound previously known to cause occupational asthma, and N-methyl-piperazine, respectively, was demonstrated by RAST, RAST inhibition and skin prick tests in 2 asthmatic subjects occupationally exposed to these agents.

摘要

通过放射性变应原吸附试验（RAST）、RAST抑制试验和皮肤点刺试验，在2名职业性接触这些制剂的哮喘患者体内，分别证实了存在针对人血清白蛋白与哌嗪（一种先前已知可引起职业性哮喘的化合物）以及N - 甲基哌嗪结合物的特异性IgE抗体。