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观点:用于检测和管理影响神经系统疾病的拉曼光谱学。

Perspective: Raman spectroscopy for detection and management of diseases affecting the nervous system.

作者信息

Robertson John L, Sayed Issa Amr, Senger Ryan S

机构信息

Department of Biomedical Engineering, Virginia Tech, Blacksburg, VA, United States.

Rametrix Technologies, Inc., Blacksburg, VA, United States.

出版信息

Front Vet Sci. 2024 Oct 21;11:1468326. doi: 10.3389/fvets.2024.1468326. eCollection 2024.

DOI:10.3389/fvets.2024.1468326
PMID:39497742
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11533901/
Abstract

Raman spectroscopy (RS) is used increasingly for disease detection, including diseases of the nervous system (CNS). This Perspective presents RS basics and how it has been applied to disease detection. Research that focused on using a novel Raman-based technology-Rametrix Molecular Urinalysis (RMU)-for systemic disease detection is presented, demonstrated by an example of how the RS/RMU technology could be used for detection and management of diseases of the CNS in companion animals.

摘要

拉曼光谱(RS)越来越多地用于疾病检测,包括神经系统(CNS)疾病。本观点阐述了拉曼光谱的基础知识及其在疾病检测中的应用方式。文中介绍了一项专注于使用基于拉曼的新型技术——拉曼矩阵分子尿液分析(RMU)——进行全身性疾病检测的研究,并通过一个实例展示了拉曼光谱/拉曼矩阵分子尿液分析技术如何用于伴侣动物中枢神经系统疾病的检测和管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8f4/11533901/94577204a06c/fvets-11-1468326-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8f4/11533901/e12964b68903/fvets-11-1468326-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8f4/11533901/94577204a06c/fvets-11-1468326-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8f4/11533901/e12964b68903/fvets-11-1468326-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8f4/11533901/94577204a06c/fvets-11-1468326-g002.jpg

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A review of clinical use of surface-enhanced Raman scattering-based biosensing for glioma.基于表面增强拉曼散射的生物传感技术在神经胶质瘤临床应用中的综述。
Front Neurol. 2024 Apr 8;15:1287213. doi: 10.3389/fneur.2024.1287213. eCollection 2024.
3
Cancer detection in dogs using rapid Raman molecular urinalysis.使用快速拉曼分子尿液分析技术在犬类中进行癌症检测。
Front Vet Sci. 2024 Feb 7;11:1328058. doi: 10.3389/fvets.2024.1328058. eCollection 2024.
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Applications of Raman spectroscopy in the diagnosis and monitoring of neurodegenerative diseases.拉曼光谱在神经退行性疾病诊断和监测中的应用。
Front Neurosci. 2024 Feb 2;18:1301107. doi: 10.3389/fnins.2024.1301107. eCollection 2024.
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Advances in Diagnostic Tools and Therapeutic Approaches for Gliomas: A Comprehensive Review.神经胶质瘤的诊断工具和治疗方法的进展:全面综述。
Sensors (Basel). 2023 Dec 15;23(24):9842. doi: 10.3390/s23249842.
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