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浓缩生长因子在根尖手术愈合结果中的作用:一例报告

Role of Concentrated Growth Factor on the Healing Outcome of Periapical Surgery: A Case Report.

作者信息

Gupta Alpa, Abraham Dax, Aggarwal Vivek, Mahesh Shakila

机构信息

Conservative Dentistry and Endodontics, Manav Rachna Dental College, Manav Rachna International Institute of Research and Studies, Faridabad, IND.

Conservative Dentistry and Endodontics, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, IND.

出版信息

Cureus. 2024 Oct 6;16(10):e70917. doi: 10.7759/cureus.70917. eCollection 2024 Oct.

Abstract

This case report highlights the use of concentrated growth factor (CGF) in enhancing healing outcomes following endodontic periapical surgery. A 57-year-old female came with pain and swelling related to chronic periapical abscesses in her lower front teeth, necessitating surgical intervention. Apicectomy combined with CGF application was considered as a treatment option. CGF, an advanced autologous platelet concentrate, offers superior healing properties due to its natural composition and absence of anticoagulants, making it a favorable option over earlier techniques like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF). The surgical procedure, performed under an operating microscope, included meticulous debridement and the placement of a CGF membrane over the surgical site. Follow-up evaluations at six months and one year demonstrated significant healing, as evident clinically and radiographically. The present case indicated the potential of CGF as an effective adjunct in periapical surgery, promoting better healing and recovery in patients with challenging dental conditions. The findings support the growing interest in autologous biomaterials for regenerative dental procedures.

摘要

本病例报告强调了浓缩生长因子(CGF)在改善牙髓根尖周手术后愈合效果方面的应用。一名57岁女性因下前牙慢性根尖周脓肿出现疼痛和肿胀,需要进行手术干预。根尖切除术联合应用CGF被视为一种治疗选择。CGF是一种先进的自体血小板浓缩物,由于其天然成分且不含抗凝剂,具有卓越的愈合特性,使其成为比富血小板血浆(PRP)和富血小板纤维蛋白(PRF)等早期技术更有利的选择。在手术显微镜下进行的手术操作包括细致的清创,并在手术部位放置CGF膜。六个月和一年后的随访评估显示出明显的愈合,临床和影像学表现均很明显。本病例表明CGF作为根尖周手术中一种有效的辅助手段具有潜力,可促进患有复杂牙齿疾病的患者更好地愈合和恢复。这些发现支持了对用于牙齿再生手术的自体生物材料的兴趣日益增长。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6442/11537772/23eee356bd48/cureus-0016-00000070917-i01.jpg

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