Blyumin-Karasik Marianna, Colon Jessica, Nguyen Sylvie, Rosen Jordan
Precision Skin & Body Institute, Davie, Florida, USA.
Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, Florida, USA.
J Cosmet Dermatol. 2025 Feb;24(2):e16668. doi: 10.1111/jocd.16668. Epub 2024 Nov 6.
Laser procedures are often used for global improvement in skin quality. The state of the skin is under stress after laser treatment, and it is beneficial to utilize topical agents to assist with optimal healing and cosmetic outcomes. Currently, such post-laser-cosmeceutical synergies are being investigated. Skin adaptogens are bioactive ingredients that enhance the skin's resistance and adaptation to stress.
Investigate the use of an adaptogenic moisturizing serum (AMS) in synergy with post-laser treatment recovery.
PATIENT/METHODS: Eight patients underwent long-pulsed 755-nm alexandrite or 1064-nm picosecond laser treatments on the face, targeting photoaging and pigmentation. After the laser treatment, during their healing process, they utilized a novel AMS twice daily to assist with the post-laser recovery. A blinded expert grader evaluated before and after facial images of each patient using a modified Griffiths photodamage photonumeric scale.
The findings revealed that the AMS was well-tolerated with no reported adverse events, and elicited aesthetically pleasing results. There was a significant decrease in photodamage scores following the treatment (p = 0.0078) with a median reduction of 3.5. Patients had improvement in skin photodamage, pigmentation, and skin radiance in clinic and photography after a combination of laser and AMS serum treatments.
Utilizing the adaptogen moisturizing serum skin care regimen after the laser treatments likely assisted in the skin's healing process. As a result, we propose that there is a potential benefit of combining certain laser treatments and an adaptogen-based skin care regimen for better aesthetic outcomes and skin recuperation post-procedure.
激光手术常用于全面改善皮肤质量。激光治疗后皮肤处于应激状态，使用外用制剂有助于实现最佳愈合和美容效果。目前，正在研究此类激光后美容药协同作用。皮肤适应原是增强皮肤对压力的抵抗力和适应能力的生物活性成分。
研究一种适应原保湿精华液（AMS）与激光治疗后恢复协同使用的效果。
患者/方法：8名患者接受了面部的长脉冲755纳米翠绿宝石激光或1064纳米皮秒激光治疗，针对光老化和色素沉着。激光治疗后，在愈合过程中，他们每天使用两次新型AMS以辅助激光后恢复。一名盲法专家评分员使用改良的格里菲斯光损伤数字评分量表评估每位患者治疗前后的面部图像。
研究结果显示，AMS耐受性良好，未报告不良事件，并产生了美观的效果。治疗后光损伤评分显著降低（p = 0.0078），中位数降低3.5。激光和AMS精华液联合治疗后，患者在临床和照片中皮肤光损伤、色素沉着和皮肤光泽均有改善。
激光治疗后使用适应原保湿精华液皮肤护理方案可能有助于皮肤的愈合过程。因此，我们提出将某些激光治疗与基于适应原的皮肤护理方案相结合可能对术后获得更好的美容效果和皮肤恢复有潜在益处。
