Miller C J, Drasar B S, Feachem R G, Hayes R J
J Hyg (Lond). 1986 Feb;96(1):49-57. doi: 10.1017/s0022172400062525.
The expression of toxigenicity by Vibrio cholerae, before and after exposure to various conditions of salinity, pH and cation composition and concentration, has been measured. Exposure to these conditions did not select for hyper- or hypo-toxigenic strains. This suggests that toxigenic V. cholerae O1 are unlikely to lose their toxigenicity when exposed to environmental stress and that V. cholerae toxin production is not a response to the stresses included in this study. These results are consistent with an aquatic reservoir for toxigenic V. cholerae O1.
已测定霍乱弧菌在暴露于不同盐度、pH值以及阳离子组成和浓度条件前后的产毒性表达。暴露于这些条件下并未筛选出高毒或低毒菌株。这表明产毒的霍乱弧菌O1在暴露于环境压力时不太可能丧失其产毒性,并且霍乱弧菌毒素的产生并非对本研究中所涉及的压力的一种反应。这些结果与产毒霍乱弧菌O1的水生储存库相一致。