School of Pharmacy, Lanzhou University, Lanzhou, 730000, People's Republic of China.
College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou, 730000, People's Republic of China.
Sci Rep. 2024 Nov 6;14(1):26927. doi: 10.1038/s41598-024-77824-6.
The impact of climate change on medicinal plants has significantly altered their suitable environments, thereby affecting the quality of herbal medicines. Notopterygium franchetii (N. franchetii), a medicinal plant intricately linked to its natural habitat, exhibits substantial quality variations influenced by the ecological conditions of its native region. In this study, comprehensive field surveys were conducted to gather occurrence records and samples of N. franchetii. The Maxent model and ArcGIS software were employed to predict the suitable habitats of N. franchetii during different time periods. A high-performance liquid chromatography (HPLC) method was developed to establish the chemical fingerprints of 21 sample batches. Fourteen common peaks were subjected to cluster analysis, principal component analysis, and orthogonal partial least squares-discriminant analysis. The findings revealed quality variations correlated with their geographic origins, identifying peaks 10, 1, 14, 3, and 4 as crucial for quality differentiation. The study indicates that precipitation, temperature, and altitude significantly influence the distribution of N. franchetii. Under current climate conditions, the suitable habitat area for N. franchetii is estimated to be approximately 94,637.33 km. However, projections under three future climate scenarios suggest a declining trend in suitable habitat areas. A quality zoning map of N. franchetii was developed, integrating a correlation model between chemical composition and environmental variables with the spatial analysis and visualization capabilities of ArcGIS. The high-quality regions for N. franchetii are predominantly located in the Gannan, Linxia, Dingxi, Longnan, and Wuwei districts. These research outcomes offer a valuable reference for identifying suitable cultivation areas and assessing the quality of N. franchetii in Gansu Province.
气候变化对药用植物的影响显著改变了它们适宜的环境，从而影响了草药的质量。羌活（Notopterygium franchetii）是一种与自然栖息地紧密相关的药用植物，其质量因原产地区的生态条件而发生显著变化。本研究通过实地调查，收集羌活的分布点和样本，运用 Maxent 模型和 ArcGIS 软件预测羌活在不同时期的适宜生境，建立了 21 批样品的高效液相色谱（HPLC）化学指纹图谱，采用聚类分析、主成分分析和正交偏最小二乘判别分析对 14 个共有峰进行分析。结果表明，羌活的质量与其地理起源有关，峰 10、1、14、3 和 4 是区分质量的关键。研究表明，降水、温度和海拔高度对羌活的分布有显著影响。在当前气候条件下，羌活的适宜生境面积约为 94637.33km。然而，在三种未来气候情景下的预测显示，羌活的适宜生境面积呈下降趋势。本研究通过整合化学组成与环境变量的相关模型、ArcGIS 的空间分析和可视化功能，制作了羌活的质量区划图，确定了羌活的高产区主要分布在甘南、临夏、定西、陇南和武威地区。这些研究结果为确定羌活的适宜种植区和评估甘肃省羌活的质量提供了有价值的参考。
