Miyake Keitaro, Hirasawa Kazuhiro, Nishimura Haruka, Tsukahara Kiyoaki
Department of Otolaryngology, Head and Neck Surgery, Todachuo General Hospital, Toda-shi 335-0023, Saitama, Japan.
Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University Hospital, Shinjuku-ku 160-0023, Japan.
World J Clin Cases. 2024 Nov 6;12(31):6506-6512. doi: 10.12998/wjcc.v12.i31.6506.
Mucosa-associated lymphoid tissue (MALT) lymphoma, a type of non-Hodgkin lymphoma, originates in the mucosal lining of body organs and internal cavities, including the nose, mouth, lungs, and digestive tract. The lymphoma develops when the body produces abnormal B lymphocytes. These lymphomas develop at the edge of the lymphoid tissue, called the marginal zone, and, hence, are classified as a type of marginal zone lymphomas. They are the most common type of marginal zone lymphomas although their occurrence is rare. To date, no previous cases of MALT lymphoma in the buccal fat pad have been reported.
We report the case of a patient who presented with a mass on the frontal cheek. Magnetic resonance imaging revealed a tumor in the buccal fat pad, and histopathological and immunohistochemical findings confirmed the diagnosis of MALT lymphoma. The patient had a history of and hepatitis C virus infection, suggesting an association between these infective agents and MALT lymphoma.
Consideration of MALT lymphoma is essential in the differential diagnosis of frontal cheek masses.
黏膜相关淋巴组织（MALT）淋巴瘤是一种非霍奇金淋巴瘤，起源于身体器官和体腔的黏膜内衬，包括鼻子、口腔、肺部和消化道。当身体产生异常B淋巴细胞时，就会发生这种淋巴瘤。这些淋巴瘤在淋巴组织边缘即边缘区发展，因此被归类为边缘区淋巴瘤的一种类型。它们是边缘区淋巴瘤中最常见的类型，尽管其发病率很低。迄今为止，尚未有颊脂垫发生MALT淋巴瘤的病例报道。
我们报告了一名患者，其额部脸颊出现肿块。磁共振成像显示颊脂垫有一个肿瘤，组织病理学和免疫组化结果证实为MALT淋巴瘤。该患者有[具体病史未给出]病史和丙型肝炎病毒感染史，提示这些感染因子与MALT淋巴瘤之间存在关联。
在额部脸颊肿块的鉴别诊断中，考虑MALT淋巴瘤至关重要。
