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胰十二指肠切除术后延迟出血的血管内治疗方法:四例病例报告

Delayed postpancreatectomy hemorrhage as the role of endovascular approach: Four case reports.

作者信息

Petrovic Igor, Romic Ivan, Alduk Ana M, Ticinovic Nino, Koltay Oliver M, Brekalo Klara, Bogut Ante

机构信息

Department of Hepatobiliary Surgery and Transplantation, University Hospital Center Zagreb, Zagreb 10000, Croatia.

Department of Surgery, University Hospital Centre Zagreb, Zagreb 10000, Croatia.

出版信息

World J Clin Cases. 2024 Nov 6;12(31):6462-6471. doi: 10.12998/wjcc.v12.i31.6462.

DOI:10.12998/wjcc.v12.i31.6462
PMID:39507121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11438700/
Abstract

BACKGROUND

Pancreatic resection is still associated with high morbidity rates and delayed postpancreatectomy hemorrhage (PPH) is the most feared complication as it may lead to hemorrhagic shock or serious septic complications. Today, endovascular approach represent safe and efficient method for minimally invasive management of extraluminal PPH.

CASE SUMMARY

We describe four patients whose postoperative recovery after pancreatic resection was complicated by postoperative pancreatic fistula (POPF) and visceral artery hemorrhage. In all cases endovascular approach was utilized and it resulted in satisfactory outcomes. We discuss modern diagnostic and therapeutic approach in this clinical scenario.

CONCLUSION

PPH is relatively uncommon, but it is a leading cause of surgical mortality after pancreatic surgery. Careful monitoring and meticulous follow-up are required for all patients post-operatively, especially in the case of confirmed POPF, which is the most significant risk factor for the development of a PPH. Angiography as a diagnostic and therapeutic method may be an optimal first-line treatment for the management of delayed PPHs. In our experience, endovascular treatment for hemorrhagic complications of pancreatic resections has shown satisfactory results.

摘要

背景

胰腺切除术的发病率仍然很高,胰十二指肠切除术后延迟出血(PPH)是最可怕的并发症,因为它可能导致失血性休克或严重的感染并发症。如今,血管内介入方法是微创治疗腔外PPH的安全有效方法。

病例总结

我们描述了4例胰腺切除术后恢复过程中并发术后胰瘘(POPF)和内脏动脉出血的患者。所有病例均采用血管内介入方法,结果令人满意。我们讨论了这种临床情况下的现代诊断和治疗方法。

结论

PPH相对少见,但它是胰腺手术后手术死亡的主要原因。所有患者术后都需要仔细监测和精心随访,尤其是在确诊为POPF的情况下,POPF是发生PPH的最重要危险因素。血管造影作为一种诊断和治疗方法可能是治疗延迟性PPH的最佳一线治疗方法。根据我们的经验,胰腺切除术后出血并发症的血管内治疗已显示出令人满意的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c2/11438700/b6bec6014675/WJCC-12-6462-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c2/11438700/37d4fc282312/WJCC-12-6462-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c2/11438700/b6bec6014675/WJCC-12-6462-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c2/11438700/37d4fc282312/WJCC-12-6462-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c2/11438700/b6bec6014675/WJCC-12-6462-g002.jpg

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本文引用的文献

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Treatment strategies to prevent or mitigate the outcome of postpancreatectomy hemorrhage: a review of randomized trials.预防或减轻胰十二指肠切除术后出血后果的治疗策略:随机试验综述
Int J Surg. 2024 Oct 1;110(10):6145-6154. doi: 10.1097/JS9.0000000000000876.
2
Systematic review of the incidence, presentation and management of gastroduodenal artery pseudoaneurysm after pancreatic resection.胰腺切除术后胃十二指肠动脉假性动脉瘤的发生率、表现和处理的系统评价。
BJS Open. 2019 Sep 30;3(6):735-742. doi: 10.1002/bjs5.50210. eCollection 2019 Dec.
3
Diagnosis and management of postpancreatectomy hemorrhage: a systematic review and meta-analysis.
胰切除术后出血的诊断和治疗:系统评价和荟萃分析。
HPB (Oxford). 2019 Aug;21(8):953-961. doi: 10.1016/j.hpb.2019.02.011. Epub 2019 Apr 6.
4
Risk Factors for Late-Onset Gastrointestinal Hemorrhage After Pancreatoduodenectomy for Pancreatic Cancer.胰腺癌胰十二指肠切除术后迟发性胃肠道出血的危险因素
World J Surg. 2019 Feb;43(2):626-633. doi: 10.1007/s00268-018-4791-7.
5
Post-pancreaticoduodenectomy hemorrhage: DSA diagnosis and endovascular treatment.胰十二指肠切除术后出血:数字减影血管造影诊断与血管内治疗
Oncotarget. 2017 Apr 27;8(43):73684-73692. doi: 10.18632/oncotarget.17450. eCollection 2017 Sep 26.
6
The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After.国际研究小组(ISGPS)术后胰瘘定义与分级的2016年更新:11年后
Surgery. 2017 Mar;161(3):584-591. doi: 10.1016/j.surg.2016.11.014. Epub 2016 Dec 28.
7
Postpancreatectomy Complications and Management.胰腺切除术后并发症及处理
Surg Clin North Am. 2016 Dec;96(6):1313-1336. doi: 10.1016/j.suc.2016.07.013.
8
Hemorrhage after Major Pancreatic Resection: Incidence, Risk Factors, Management, and Outcome.胰腺大部切除术后出血:发生率、危险因素、处理及结局
Scand J Surg. 2017 Mar;106(1):47-53. doi: 10.1177/1457496916631854. Epub 2016 Jul 8.
9
Evolution in the Treatment of Delayed Postpancreatectomy Hemorrhage: Surgery to Interventional Radiology.胰十二指肠切除术后延迟出血治疗的演变:从手术到介入放射学。
Pancreas. 2015 Aug;44(6):953-8. doi: 10.1097/MPA.0000000000000347.
10
Arterial pseudoaneurysms following hepato-pancreato-biliary surgery: a single center experience.肝胰胆手术后的动脉假性动脉瘤:单中心经验
JOP. 2015 Jan 31;16(1):85-9. doi: 10.6092/1590-8577/2907.