Rezaei Fatemeh, Mazidimoradi Afrooz, Pasokh Zahra, Mobasheri Farzaneh, Taheri Mohammad, Salehiniya Hamid, Allahqoli Leila, Alkatout Ibrahim
Research Center for Social Determinants of Health Jahrom University of Medical Sciences Jahrom Iran.
Shiraz University of Medical Sciences Shiraz Iran.
Aging Med (Milton). 2024 Oct 14;7(5):614-635. doi: 10.1002/agm2.12366. eCollection 2024 Oct.
This study describes the 2010-2019 trend of cervical cancer (CC) in women over 55 by socio-demographic index (SDI) and geographical regions.
We obtained data on CC annually from 2010 to 2019 from the 2019 Global Burden of Disease Study (GBD) to analyze the incidence, death and prevalence rates, and disability-adjusted life years (DALYs) associated with CC across different parameters such as global trend, age groups, SDI, continents, World Bank Regions, World Health Organization (WHO) regions, GBD regions, and National and territorial division. This analysis covers data from 204 countries and territories from 1990 to 2019.
There were 236,228 CC incidence cases worldwide in 2019, which is a 1.27-fold increase from 2010. Global CC deaths also increased to 169,304 cases in 2019, reflecting a 1.24-fold increase. CC prevalence increased to 769,925 cases in 2019, representing a 1.4-fold rise. The number of CC DALYs globally increased to 3,835,979 cases in 2019, reflecting a 1.24-fold increase. Incidence, death, prevalence, and DALY numbers of CC increased across all age groups females in the 65-69 years age group experienced the highest increase. Middle SDI countries had the highest incidence, death, prevalence, and DALY numbers, while low SDI countries showed increasing trends. Asia exhibited the highest incidence, death, prevalence, and DALY numbers of CC. Upper middle-income countries had the highest incidence, death, prevalence, and DALY numbers, with the highest decreases in these rates except the prevalence rate. The Western Pacific Region showed the highest incidence, death, prevalence, and DALY numbers, with declining rate trends. The Republic of Kiribati showed the highest incidence, death, prevalence, and DALY numbers.
Based on the study results, it is clear that although the global trend of epidemiological indicators of CC is decreasing, the largest proportion of the decreasing trend is related to developing countries. But in regions of Africa and Asia that have a lower level of development, sometimes these indicators show upward trends, which shows the worsening of the problem in these regions and the need for serious policies and plans to implement comprehensive vaccination, screening, and promotion interventions. People's awareness is necessary in the field of better disease control.
本研究描述了2010 - 2019年55岁以上女性宫颈癌（CC）按社会人口指数（SDI）和地理区域划分的趋势。
我们从《2019年全球疾病负担研究》（GBD）中获取了2010年至2019年每年的宫颈癌数据，以分析发病率、死亡率、患病率以及与宫颈癌相关的伤残调整生命年（DALYs），涉及不同参数，如全球趋势、年龄组、SDI、各大洲、世界银行区域、世界卫生组织（WHO）区域、GBD区域以及国家和领土划分。该分析涵盖了1990年至2019年来自204个国家和地区的数据。
2019年全球有236,228例宫颈癌发病病例，较2010年增长了1.27倍。2019年全球宫颈癌死亡病例也增至169,304例，增长了1.24倍。2019年宫颈癌患病率增至769,925例，增长了1.4倍。2019年全球宫颈癌伤残调整生命年数增至3,835,979例，增长了1.24倍。各年龄组女性的宫颈癌发病率、死亡率、患病率和伤残调整生命年数均有所上升，其中65 - 69岁年龄组增长幅度最大。中等SDI国家的发病率、死亡率、患病率和伤残调整生命年数最高，而低SDI国家呈上升趋势。亚洲的宫颈癌发病率、死亡率、患病率和伤残调整生命年数最高。中高收入国家的发病率、死亡率、患病率和伤残调整生命年数最高，除患病率外，这些比率下降幅度最大。西太平洋地区的发病率、死亡率、患病率和伤残调整生命年数最高，且呈下降趋势。基里巴斯共和国的发病率、死亡率、患病率和伤残调整生命年数最高。
根据研究结果，很明显，尽管宫颈癌流行病学指标的全球趋势在下降，但下降趋势的最大部分与发展中国家有关。但在非洲和亚洲发展水平较低的地区，有时这些指标呈上升趋势，这表明这些地区问题的恶化，需要制定认真的政策和计划来实施全面的疫苗接种、筛查和推广干预措施。在更好地控制疾病领域，提高人们的认识是必要 的。
