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老年桡骨远端骨折的手术治疗与保守治疗:一项系统评价和Meta分析

Surgical vs. Conservative Treatment of Distal Radius Fractures in the Elderly: A Systematic Review and Meta-Analysis.

作者信息

Alanazi Abdulelah A, Alsharari Abdulkarim M, Alrumaih Nawaf H, Alsudays Aseel I, Alanazi Amer K, Alhilali Mohamed, Bo Shagea Fatemah, Al-Rawaf Mohammed M, Alsiwat Faisal J

机构信息

Orthopedic Surgery, King Saud Medical City, Riyadh, SAU.

Physiotherapy and Health Rehabilitation, Jouf University, Sakaka, SAU.

出版信息

Cureus. 2024 Dec 17;16(12):e75879. doi: 10.7759/cureus.75879. eCollection 2024 Dec.

Abstract

Elderly patients with distal radius fractures (DRFs) pose a significant medical challenge due to their high incidence and related healthcare costs. Both surgical methods like volar plate fixation and conservative approaches such as casting are common, yet their relative effectiveness remains unclear. This review and meta-analysis compare surgical and conservative treatments, focusing on wrist functionality, upper extremity performance, grip strength, and pain after one year. A literature search was conducted in PubMed, Cochrane Library, Scopus, and Web of Science up to November 6, 2024, to find randomized controlled trials (RCTs) for DRFs in patients aged 65 and older. Thirteen RCTs with 2400 participants were included. After one year, there was no significant difference in wrist function between groups (mean difference (MD)=-1.24; 95% confidence interval (CI) -2.61 to 0.13; p=0.78; I²=78%), but upper limb function favored surgery as measured by the Disabilities of the Arm, Shoulder, and Hand (DASH) score (MD=-2.32; 95% CI -3.66 to -0.98; p=0.0007; I²=83%). Surgical treatment significantly improved grip strength (MD=3.82; 95% CI 1.55 to 6.09; p=0.001) but resulted in higher pain levels (MD=2.73; 95% CI 1.16 to 4.31; p=0.0007). Results showed substantial heterogeneity and publication bias. Surgical treatment offers slight functional advantages in grip strength and DASH scores but is associated with higher pain; conservative treatment remains viable with minimal differences in long-term wrist function. Further high-quality studies are necessary to address heterogeneity and publication bias.

摘要

桡骨远端骨折(DRF)的老年患者因其高发病率和相关医疗费用而构成重大医学挑战。诸如掌侧钢板固定等手术方法和诸如石膏固定等保守方法都很常见,但其相对有效性仍不明确。本综述和荟萃分析比较了手术治疗和保守治疗,重点关注一年后的手腕功能、上肢表现、握力和疼痛情况。截至2024年11月6日,在PubMed、Cochrane图书馆、Scopus和科学网进行了文献检索,以查找65岁及以上患者DRF的随机对照试验(RCT)。纳入了13项随机对照试验,共2400名参与者。一年后,两组之间的手腕功能无显著差异(平均差(MD)=-1.24;95%置信区间(CI)-2.61至0.13;p=0.78;I²=78%),但根据手臂、肩部和手部功能障碍(DASH)评分衡量,上肢功能更倾向于手术治疗(MD=-2.32;95%CI-3.66至-0.98;p=0.0007;I²=83%)。手术治疗显著提高了握力(MD=3.82;95%CI 1.55至6.09;p=0.001),但导致疼痛程度更高(MD=2.73;95%CI 1.16至4.31;p=0.0007)。结果显示存在显著的异质性和发表偏倚。手术治疗在握力和DASH评分方面具有轻微的功能优势,但与更高的疼痛相关;保守治疗在长期手腕功能上差异最小,仍然可行。需要进一步的高质量研究来解决异质性和发表偏倚问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c25b/11700016/495aec00c56c/cureus-0016-00000075879-i01.jpg

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