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溃疡性结肠炎女性 pouch 手术后的生育能力:机器人手术是获得更好结果的关键吗?

Fertility after pouch surgery in women with ulcerative colitis: Is robotic surgery the key to better outcomes?

机构信息

Medical Sciences Postgraduate Program, School of Medicine, University of Brasilia, Federal District, Brasilia, Brazil.

Department of Colorectal Surgery, University Hospital of Brasília, Brasília, Brazil.

出版信息

Womens Health (Lond). 2024 Jan-Dec;20:17455057241294219. doi: 10.1177/17455057241294219.

DOI:10.1177/17455057241294219
PMID:39508620
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11544681/
Abstract

Fertility preservation is a major concern for women with ulcerative colitis who require surgical treatment. Previous studies have shown that the risk of infertility after restorative proctocolectomy is approximately four times higher. However, this risk appears to be lower in patients who undergo minimally invasive approaches, such as laparoscopic surgery. The benefits of laparoscopy have led to a debate on whether robotic-assisted surgery could offer better results in terms of fertility. Surgical robotic platforms can provide improved visualization of the pelvis and more precise dissection of anatomical structures. In theory, this could reduce tissue damage and the inflammatory response, leading to lower adhesion formation and fallopian tube blockage, thereby preserving fertility.

摘要

生育力保存是溃疡性结肠炎女性患者在需要手术治疗时的一个主要关注点。既往研究表明,接受直肠结肠切除术(restorative proctocolectomy)后的不孕风险大约增加四倍。然而,对于采用微创方法(如腹腔镜手术)的患者,该风险似乎较低。腹腔镜手术的优势使得人们开始争论机器人辅助手术是否在生育力方面能提供更好的结果。手术机器人平台可以提供骨盆更好的可视化效果,更精准地解剖解剖结构。理论上,这可以减少组织损伤和炎症反应,从而减少粘连形成和输卵管阻塞,进而保存生育力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3dd/11544681/187eceb3db43/10.1177_17455057241294219-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3dd/11544681/187eceb3db43/10.1177_17455057241294219-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3dd/11544681/187eceb3db43/10.1177_17455057241294219-fig1.jpg

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本文引用的文献

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Surgical and Fertility Outcomes of Reduced-Port Robotic Myomectomy: A Single-Center Experience of 401 Cases.减孔机器人子宫肌瘤切除术的手术及生育结局:单中心401例经验
J Clin Med. 2024 Mar 21;13(6):1807. doi: 10.3390/jcm13061807.
2
Multi-Port Robotic-Assisted Laparoscopic Myomectomy: A Systematic Review and Meta-Analysis of Comparative Clinical and Fertility Outcomes.多端口机器人辅助腹腔镜子宫肌瘤切除术:比较临床和生育结局的系统评价与荟萃分析
J Clin Med. 2023 Jun 19;12(12):4134. doi: 10.3390/jcm12124134.
3
An early experience in robotic ileoanal pouch surgery with robotic intracorporeal single-stapled anastomosis (RiSSA) at a tertiary referral centre.
在一家三级转诊中心,使用机器人辅助经体内单吻合器吻合技术(RiSSA)进行机器人回肠贮袋肛管吻合术的早期经验。
Colorectal Dis. 2023 Jun;25(6):1169-1175. doi: 10.1111/codi.16528. Epub 2023 Mar 11.
4
European Crohn's and Colitis Guidelines on Sexuality, Fertility, Pregnancy, and Lactation.欧洲克罗恩病和结肠炎学会关于性、生育、妊娠及哺乳的指南
J Crohns Colitis. 2023 Jan 27;17(1):1-27. doi: 10.1093/ecco-jcc/jjac115.
5
The impact of the ileoanal pouch on female fertility in ulcerative colitis: A systematic review and meta-analysis.回肠肛管袋对溃疡性结肠炎女性生育能力的影响:一项系统评价和荟萃分析。
Colorectal Dis. 2022 Aug;24(8):918-924. doi: 10.1111/codi.16123. Epub 2022 Apr 8.
6
Robotic Surgery for Ulcerative Colitis.溃疡性结肠炎的机器人手术
Clin Colon Rectal Surg. 2022 Jan 17;34(5):292-296. doi: 10.1055/s-0041-1726447. eCollection 2021 Sep.
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ECCO Guidelines on Therapeutics in Ulcerative Colitis: Surgical Treatment.ECCO 指南:溃疡性结肠炎治疗——手术治疗
J Crohns Colitis. 2022 Feb 23;16(2):179-189. doi: 10.1093/ecco-jcc/jjab177.
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The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Surgical Management of Ulcerative Colitis.美国结肠和直肠外科医师协会关于溃疡性结肠炎外科治疗的临床实践指南。
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Women's Health and Ulcerative Colitis.女性健康与溃疡性结肠炎。
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