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撤回声明:营养类黄酮调节雌激素受体α信号传导。

RETRACTION: Nutritional Flavonoids Modulate Estrogen Receptor α Signaling.

出版信息

IUBMB Life. 2025 Jan;77(1):e2926. doi: 10.1002/iub.2926. Epub 2024 Nov 7.

DOI:10.1002/iub.2926
PMID:39509549
Abstract

F. Virgili , F. Acconcia , R. Ambra , A. Rinna , P. Totta , and M. Marino , "Nutritional Flavonoids Modulate Estrogen Receptor α Signaling," IUBMB Life 56, no. 3 (2004): 145-151, https://doi.org/10.1080/15216540410001685083. The above article, published online on 3 January 2008 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Efstathios S. Gonos; the International Union of Biochemistry and Molecular Biology; and Wiley Periodicals LLC. The retraction has been agreed due to concerns raised by third parties on the data presented in the article. Specifically, duplication of several Western Blot bands has been detected within Figure 2a. The relative raw data could no longer be accessed due to the considerable time elapsed since the article's publication. The corresponding author, Maria Marino, maintains that the concerns do not impact the overall results and conclusions of the study, and disagrees with the decision of retraction. However, the article is retracted as the editors have lost trust in the integrity of the data presented and consider the conclusions invalid.

摘要

F. 维尔吉利、F. 阿孔恰、R. 安布拉、A. 林纳、P. 托塔和M. 马里诺,“营养类黄酮调节雌激素受体α信号传导”,《国际生物化学与分子生物学联盟生活》第56卷,第3期(2004年):145 - 151页,https://doi.org/10.1080/15216540410001685083 。上述文章于2008年1月3日在线发表于威利在线图书馆(wileyonlinelibrary.com),已由期刊主编埃夫斯塔西奥斯·S. 戈诺斯、国际生物化学与分子生物学联盟以及威利期刊有限责任公司协商一致撤回。撤回是由于第三方对文章中呈现的数据提出担忧。具体而言,在图2a中检测到几条蛋白质免疫印迹条带存在重复。由于文章发表后已过去相当长的时间,相关的原始数据已无法再获取。通讯作者玛丽亚·马里诺坚称这些担忧并不影响该研究的总体结果和结论,不同意撤回的决定。然而,该文章仍被撤回,因为编辑们对所呈现数据的完整性失去了信任,并认为结论无效。

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