Teng Y S, Jehan S, Lie-Injo L E
Hum Genet. 1979;53(1):87-90. doi: 10.1007/BF00289455.
Human alcohol dehydrogenase ADH2 and ADH3 were investigated in liver and stomach specimens of Chinese and Indians from West Malaysia. Eight-nine percent of the Chinese carry the atypical ADH2 type, a proportion very similar to that reported in Japanese. However, among 43 Indian specimens there was not a single case of atypical ADH2. In Indians, the gene frequency of ADH13 is 0.64 and of ADH23 0.36, similar to the frequencies in Caucasians, whereas in Chinese, the gene frequency for ADH13 and ADH23 is 0.91 and 0.09, respectively. We also report some unusual enzymatic characteristics in the course of our study.
对来自马来西亚西部的中国人和印度人的肝脏和胃标本中的人类乙醇脱氢酶ADH2和ADH3进行了研究。89%的中国人携带非典型ADH2型，这一比例与在日本人中报道的非常相似。然而，在43份印度标本中，没有一例非典型ADH2。在印度人中，ADH13的基因频率为0.64，ADH23的基因频率为0.36，与高加索人的频率相似，而在中国人中，ADH13和ADH23的基因频率分别为0.91和0.09。在我们的研究过程中，我们还报告了一些不寻常的酶学特征。
