Department of Internal Medicine, Emergency Medicine Section, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Department of Emergency Medicine, Tawam Hospital, Al Ain, United Arab Emirates.
JMIR Res Protoc. 2024 Nov 12;13:e58780. doi: 10.2196/58780.
: Globally, there is significant variation in the out-of-hospital cardiac arrest (OHCA) survival rate. Early links in the chain of survival, including bystander cardiopulmonary resuscitation (CPR) and the use of an automated external defibrillator at the scene, are known to be of crucial importance, with strong evidence of increased survival rate with good neurological outcomes. The data from the Middle East are limited and report variable rates of bystander CPR and survival. It is crucial to get prospective, reliable data on bystander response in these regions to help plan interventions to improve bystander response and outcomes.
This international collaborative study aims to describe the characteristics, including bystander interventions and outcomes, of OHCAs brought to hospitals enrolled in the study from Abu Dhabi, United Arab Emirates; Doha, Qatar; and Muscat, Oman. It also aims to describe the strength of the association between bystander response and OHCA outcomes, including the return of spontaneous circulation, survival to hospital admission, survival to discharge, and good neurological outcome at discharge in the local context of low bystander CPR rates.
This multicenter, prospective, noninterventional observational study (Bro. Study) will be conducted at the emergency departments of 4 participating tertiary care hospitals in 3 countries. The data will be collected prospectively according to the Utstein style (a set of internationally accepted guidelines for uniform reporting of cardiac arrests) on demographic variables (age, sex, nationality, country, participating center, and comorbidities), peri-cardiac arrest variables (location, witnessed or not, bystander CPR, use of automated external defibrillator, time of emergency medical services arrival, initial rhythm, number of shocks, and time of prehospital CPR), and outcome variables (return of spontaneous circulation, survival to discharge, and neurological outcome at discharge and 3 months). Univariate and multivariate analysis with logistic regression models will be used to measure the strength of the association of bystander interventions with outcomes using SPSS (version 22).
Data collection began in November 2023 and will continue for 2 years, with publication expected by early 2026.
Bystander response to an OHCA is critical to a favorable outcome. The reliable, baseline bystander CPR data will be a cornerstone in the team's next planned projects, which are to qualitatively identify the barriers to bystander CPR, conduct a scoping review of community interventions in the Gulf and other Asian countries, and design and implement strategies to help improve the bystander CPR rate in the community.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/58780.
在全球范围内，院外心脏骤停（OHCA）的存活率存在显著差异。生存链中的早期环节，包括旁观者心肺复苏（CPR）和在现场使用自动体外除颤器，被认为至关重要，有强有力的证据表明，良好的神经功能结局与存活率的提高有关。来自中东的数据有限，报告的旁观者 CPR 和存活率各不相同。获得这些地区旁观者反应的前瞻性、可靠数据对于计划干预措施以提高旁观者反应和结局至关重要。
这项国际合作研究旨在描述从阿拉伯联合酋长国阿布扎比、卡塔尔多哈和阿曼马斯喀特送入研究中纳入的医院的 OHCA 的特征，包括旁观者干预措施和结局。它还旨在描述旁观者反应与 OHCA 结局之间的关联强度，包括在旁观者 CPR 率较低的情况下，自主循环恢复、入院存活率、出院存活率和出院时良好的神经功能结局。
这项多中心、前瞻性、非干预性观察研究（Bro. 研究）将在 3 个国家的 4 家参与的三级护理医院的急诊科进行。将根据乌斯丁风格（一套国际公认的心脏骤停报告统一标准）前瞻性地收集人口统计学变量（年龄、性别、国籍、国家、参与中心和合并症）、心脏骤停前变量（地点、是否目击、旁观者 CPR、使用自动体外除颤器、紧急医疗服务到达时间、初始节律、电击次数和院前 CPR 时间）和结局变量（自主循环恢复、出院存活率和出院时及 3 个月时的神经功能结局）的数据。将使用 SPSS（版本 22）的逻辑回归模型进行单变量和多变量分析，以衡量旁观者干预与结局之间的关联强度。
数据收集于 2023 年 11 月开始，将持续 2 年，预计 2026 年初发表。
旁观者对 OHCA 的反应对良好的结局至关重要。可靠的、基线旁观者 CPR 数据将是团队下一个计划项目的基石，这些项目将定性地确定旁观者 CPR 的障碍，对海湾和其他亚洲国家的社区干预措施进行范围综述，并设计和实施策略，以帮助提高社区中旁观者 CPR 的比率。
国际注册报告标识符（IRRID）：DERR1-10.2196/58780。
