Young Kelly Z, Loveless Ian, Su Wan-Ting K, Veenstra Jesse, Yin Congcong, Dimitrion Peter, Krevh Rachel, Zhou Li, She Ruicong, Pan Mingming, Levin Albert M, Young Albert, Samir Eglal, Dai Andrea, Ge James, Huggins Richard H, de Guzman Strong Cristina, Lim Henry W, Ozog David M, Hamzavi Iltefat, Adrianto Indra, Mi Qing-Sheng
Center for Cutaneous Biology and Immunology Research, Department of Dermatology, Henry Ford Health, Detroit, Michigan.
Center for Cutaneous Biology and Immunology Research, Department of Dermatology, Henry Ford Health, Detroit, Michigan; Center for Bioinformatics, Department of Public Health Sciences, Henry Ford Health, Detroit, Michigan; Department of Epidemiology and Biostatistics, College of Human Medicine, Michigan State University, East Lansing, Michigan.
J Am Acad Dermatol. 2025 Mar;92(3):487-494. doi: 10.1016/j.jaad.2024.10.073. Epub 2024 Nov 10.
Most epidemiological studies of hidradenitis suppurativa (HS) have described homogeneous patient populations.
To characterize demographics, modifiable health behaviors, and comorbidities of HS patients within a diverse cohort.
A retrospective cross-sectional study of 13,130 HS patients within a health care system was conducted.
A female sex bias of ∼3:1 in all racial/ethnic subgroups was observed. Black/African American (AA) patients had a lower age at HS diagnosis than White patients (37.1 years vs 39.4 years, P < .001). A higher proportion of Black/AA females than White females with HS had body mass index in the obese range (69.9% vs 56.5%; P = .03). In contrast, fewer Black/AA males with HS had a body mass index in the obese range compared to White males (51.4% vs 61.0%; P < .001). More Black/AA patients than White patients with HS had congestive heart failure (odds ratio (OR) = 2.10, confidence interval (CI) = 1.19-3.78; P < .05), chronic pulmonary disease (OR = 1.34; CI = 1.02-1.78; P < .05), diabetes with chronic complication (OR = 1.73; CI = 1.16-2.60; P < .05), renal disease (OR = 2.66; CI = 1.67-4.34; P < .05), and Charlson comorbidity index score ≥4 (OR = 1.67; CI = 1.09-2.58; P < .05). Furthermore, male patients were more likely than female patients to have renal disease (OR = 2.62; CI = 1.66-4.14; P < .05).
A single-center study.
Subgroups of HS patients had significant differences in demographics, risk factors, and comorbid conditions.
大多数化脓性汗腺炎（HS）的流行病学研究描述的是同质化的患者群体。
在一个多样化队列中描述HS患者的人口统计学特征、可改变的健康行为和合并症。
对一个医疗系统内的13130例HS患者进行了一项回顾性横断面研究。
在所有种族/族裔亚组中均观察到约3:1的女性性别偏差。黑人/非裔美国人（AA）患者HS诊断时的年龄低于白人患者（37.1岁对39.4岁，P <.001）。患有HS的黑人/AA女性肥胖范围内体重指数的比例高于白人女性（69.9%对56.5%；P = 0.03）。相比之下，患有HS的黑人/AA男性肥胖范围内体重指数的比例低于白人男性（51.4%对61.0%；P <.001）。患有HS的黑人/AA患者比白人患者有更多的充血性心力衰竭（优势比（OR）= 2.10，置信区间（CI）= 1.19 - 3.78；P <.05）、慢性肺病（OR = 1.34；CI = 1.02 - 1.78；P <.05）、伴有慢性并发症的糖尿病（OR = 1.73；CI = 1.16 - 2.60；P <.05）、肾病（OR = 2.66；CI = 1.67 - 4.34；P <.05）以及Charlson合并症指数评分≥4（OR = 1.67；CI = 1.09 - 2.58；P <.05）。此外，男性患者比女性患者更易患肾病（OR = 2.62；CI = 1.66 - 4.14；P <.05）。
单中心研究。
HS患者亚组在人口统计学、危险因素和合并症方面存在显著差异。
