IS3整合到IS2中会产生短序列重复。
Integration of IS3 into IS2 generates a short sequence duplication.
作者信息
Sommer H, Cullum J, Saedler H
出版信息
Mol Gen Genet. 1979;177(1):85-9. doi: 10.1007/BF00267256.
PMID:395417
Abstract
The Gal+ allele IS2-43 is known to segregate Gal- clones. Among 11 Gal- segregants, one was shown to be due to the integration of IS3 into IS2-43. Precise excision of the integrated IS3 element occurred at a rate of 5 x 10(-9)/cell/generation. DNA sequence analysis revealed that the termini of the IS3 element have the relation of imperfect inverted repeats and it is now flanked by a 3bp or 4bp duplication, a size which has not been seen before with other elements.
摘要
已知Gal+等位基因IS2 - 43会分离出Gal-克隆。在11个Gal-分离株中，有一个被证明是由于IS3整合到IS2 - 43中所致。整合的IS3元件的精确切除发生率为5×10(-9)/细胞/代。DNA序列分析表明，IS3元件的末端具有不完全反向重复关系，现在其两侧有3bp或4bp的重复序列，这是其他元件以前未曾见过的大小。
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