Shahinfar Hossein, Payandeh Nastaran, Zeraattalab-Motlagh Sheida, Torabynasab Kimia, Jayedi Ahmad, Ejtahed Haniehsadat, Hasani-Ranjbar Shirin, Shab-Bidar Sakineh
Department of Nutrition, School of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran.
Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
Int J Obes (Lond). 2025 Apr;49(4):578-585. doi: 10.1038/s41366-024-01673-6. Epub 2024 Nov 14.
There is a lack of clarity on the comparative effects of different beverages on weight loss in adults.
This study aimed at quantifying and ranking the effects of different beverages on weight loss.
We searched PubMed, Scopus, and Web of Science up to January 2023. We included randomized trials evaluating the comparative effects of two or more beverages, or compared a beverage against a control group (water, no intervention), for weight loss in adults. We conducted a random-effects network meta-analysis (NMA) with a Bayesian framework to estimate mean difference [MD] and 95% credible interval [CrI].
In total, 78 randomized trials with 4168 participants were eligible. Low/no-calorie sweetened beverages (LNCSB) was effective for weight loss compared with water (MD: -0.79 kg, 95% CrI: -1.35, -0.18), milk (MD: -0.80 kg, 95% CrI: -1.59, -0.01), fruit juice (MD: -0.83 kg, 95% CrI: -1.47, -0.13), sugar-sweetened beverages (SSB) (MD: -1.08 kg, 95% CrI: -1.65, -0.50), and no intervention (MD: -1.19 kg, 95% CrI: -1.93, -0.41). However, in sensitivity analyses, no significant effect was seen in trials with a low risk of bias and those that implemented calorie restriction. LNCSB drinking was effective for waist circumference reduction compared with water (MD: -1.85 cm, 95% CrI: -3.47, -0.22). The certainty of evidence from most comparisons was rated low.
This study suggested evidence of low certainty that intake of LNCSBs can result in a small weight loss when used as a substitute for other beverages. Considering the low certainty of evidence, more research is needed to compare the effects of different beverages on body weight.
Not applicable, but the protocol of this systematic review was registered at PROSPERO (registration number: CRD42023407937).
不同饮料对成年人减肥的比较效果尚不清楚。
本研究旨在量化并排序不同饮料对减肥的效果。
我们检索了截至2023年1月的PubMed、Scopus和Web of Science数据库。我们纳入了评估两种或更多饮料的比较效果，或比较一种饮料与对照组（水、无干预）对成年人减肥效果的随机试验。我们采用贝叶斯框架进行随机效应网络荟萃分析（NMA），以估计平均差[MD]和95%可信区间[CrI]。
总共78项随机试验、4168名参与者符合条件。与水（MD：-0.79千克，95% CrI：-1.35，-0.18）、牛奶（MD：-0.80千克，95% CrI：-1.59，-0.01）、果汁（MD：-0.83千克，95% CrI：-1.47，-0.13）、含糖饮料（SSB）（MD：-1.08千克，95% CrI：-1.65，-0.50）和无干预（MD：-1.19千克，95% CrI：-1.93，-0.41）相比，低热量/不含热量的甜味饮料（LNCSB）对减肥有效。然而，在敏感性分析中，在偏倚风险低的试验和实施热量限制的试验中未观察到显著效果。与水相比，饮用LNCSB对减小腰围有效（MD：-1.85厘米，95% CrI：-3.47，-0.22）。大多数比较的证据确定性被评为低。
本研究表明，证据确定性低，即当LNCSB用作其他饮料的替代品时，其摄入可导致少量体重减轻。考虑到证据的低确定性，需要更多研究来比较不同饮料对体重的影响。
不适用，但本系统评价的方案已在PROSPERO注册（注册号：CRD42023407937）。
