• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

北极地区测量污染物的健康影响：简短交流。

Health effects associated with measured contaminants in the Arctic: short communication.

机构信息

Centre for Arctic Health & Molecular Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark.

Greenland Center for Health Research, University of Greenland, Nuussuaq, Greenland.

出版信息

Int J Circumpolar Health. 2024 Dec;83(1):2425467. doi: 10.1080/22423982.2024.2425467. Epub 2024 Nov 17.

DOI:10.1080/22423982.2024.2425467
PMID:39552042
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11574950/
Abstract

The Arctic Monitoring Assessment Program Human Health Assessment report 2021 presents a summary of the presence of environmental contaminants in human populations across the circumpolar Arctic and related health effects. Based on this report the objective of this paper is giving a short summary of the health effects related to the current level of persistent organic pollutants (POP) and metals. The overall key findings are as follows: i. metals and POP (polychlorinated biphenyls, per- and polyfluoroalkyl substances (PFAS)) in the Arctic have known adverse health impacts on humans especially on developing foetuses and children. Lifestyle, diet and nutrition and genetics influence the risk; ii. POP and metals negatively impact the brain and immune system, increasing the risk of childhood obesity, type 2 diabetes later in life and negatively affect foetal growth and development: iii. marine food omega-3 fatty acids can diminish adverse effects of high mercury exposure on cardiovascular and neurological outcomes; iv. the interaction of genetic, lifestyle, nutrition status and contaminants can influence the risk of cancer, metabolic disease, nervous system disorders, disruption of reproduction and foetal and child growth. Future investigations must focus on genetically and effect modifiers and mixtures of POP exposures to explore the effect of chemical interaction on health outcomes.

摘要

北极监测评估计划人类健康评估报告 2021 年概述了环北极地区人类群体中环境污染物的存在及其相关健康影响。基于该报告，本文的目的是简要总结与当前持久性有机污染物 (POP) 和金属水平相关的健康影响。总体主要发现如下：i. 北极的金属和 POP（多氯联苯、全氟和多氟烷基物质 (PFAS)）对人类健康有已知的不良影响，尤其是对发育中的胎儿和儿童。生活方式、饮食和营养以及遗传因素会影响风险；ii. POP 和金属会对大脑和免疫系统造成负面影响，增加儿童肥胖、成年后患 2 型糖尿病的风险，并对胎儿的生长和发育产生负面影响；iii. 海洋食物中的 omega-3 脂肪酸可以减少高汞暴露对心血管和神经结果的不利影响；iv. 遗传、生活方式、营养状况和污染物的相互作用会影响癌症、代谢疾病、神经系统疾病、生殖障碍以及胎儿和儿童生长的风险。未来的研究必须集中在基因和效应修饰剂以及 POP 暴露的混合物上，以探索化学相互作用对健康结果的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/1b85b1081bcf/ZICH_A_2425467_F0011_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/53e1478edbea/ZICH_A_2425467_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/8cd2de81981f/ZICH_A_2425467_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/9820d3b61edd/ZICH_A_2425467_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/1498eedcd79a/ZICH_A_2425467_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/7f3442cd4b5f/ZICH_A_2425467_F0005_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/3ba952136b61/ZICH_A_2425467_F0006_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/91307efe8cb0/ZICH_A_2425467_F0007_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/f35a730f5fc1/ZICH_A_2425467_F0008_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/f888b3ccb99d/ZICH_A_2425467_F0009_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/8b37a06b38a1/ZICH_A_2425467_F0010_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/1b85b1081bcf/ZICH_A_2425467_F0011_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/53e1478edbea/ZICH_A_2425467_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/8cd2de81981f/ZICH_A_2425467_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/9820d3b61edd/ZICH_A_2425467_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/1498eedcd79a/ZICH_A_2425467_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/7f3442cd4b5f/ZICH_A_2425467_F0005_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/3ba952136b61/ZICH_A_2425467_F0006_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/91307efe8cb0/ZICH_A_2425467_F0007_B.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/f35a730f5fc1/ZICH_A_2425467_F0008_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/f888b3ccb99d/ZICH_A_2425467_F0009_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/8b37a06b38a1/ZICH_A_2425467_F0010_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01eb/11574950/1b85b1081bcf/ZICH_A_2425467_F0011_OC.jpg

相似文献

1
Health effects associated with measured contaminants in the Arctic: short communication.北极地区测量污染物的健康影响：简短交流。
Int J Circumpolar Health. 2024 Dec;83(1):2425467. doi: 10.1080/22423982.2024.2425467. Epub 2024 Nov 17.
2
Diet, lifestyle and contaminants in three east Greenland Inuit municipalities.格陵兰岛东部三个因纽特人自治市的饮食、生活方式与污染物
Chemosphere. 2023 Dec;344:140368. doi: 10.1016/j.chemosphere.2023.140368. Epub 2023 Oct 4.
3
Environmental contaminants in Arctic human populations: Trends over 30 years.北极地区人类群体中的环境污染物：30 多年来的趋势。
Environ Int. 2024 Jul;189:108777. doi: 10.1016/j.envint.2024.108777. Epub 2024 May 25.
4
Exposure and effects assessment of persistent organohalogen contaminants in arctic wildlife and fish.北极野生动物和鱼类中持久性有机卤代污染物的暴露和影响评估。
Sci Total Environ. 2010 Jul 1;408(15):2995-3043. doi: 10.1016/j.scitotenv.2009.10.038. Epub 2009 Nov 12.
5
Levels and trends of metals in human populations living in the Arctic.北极地区人群体内金属元素的含量和趋势。
Int J Circumpolar Health. 2024 Dec;83(1):2386140. doi: 10.1080/22423982.2024.2386140. Epub 2024 Aug 22.
6
Levels and trends of persistent organic pollutants in human populations living in the Arctic.北极地区居住人群体内持久性有机污染物的水平和趋势。
Int J Circumpolar Health. 2024 Dec;83(1):2392405. doi: 10.1080/22423982.2024.2392405. Epub 2024 Sep 17.
7
Association between environmental contaminants and health outcomes in indigenous populations of the Circumpolar North.北极圈北部原住民群体中环境污染物与健康结果之间的关联。
Int J Circumpolar Health. 2014 Dec 5;73(1):25808. doi: 10.3402/ijch.v73.25808. eCollection 2014.
8
Human health implications of environmental contaminants in Arctic Canada: A review.加拿大北极地区环境污染物对人类健康的影响：综述
Sci Total Environ. 2005 Dec 1;351-352:165-246. doi: 10.1016/j.scitotenv.2005.03.034. Epub 2005 Nov 16.
9
State of knowledge on current exposure, fate and potential health effects of contaminants in polar bears from the circumpolar Arctic.环极北极地区北极熊当前污染物暴露、归宿和潜在健康影响的知识现状。
Sci Total Environ. 2019 May 10;664:1063-1083. doi: 10.1016/j.scitotenv.2019.02.030. Epub 2019 Feb 5.
10
Environmental contaminants and human health in the Canadian Arctic.加拿大北极地区的环境污染物和人类健康
Sci Total Environ. 2010 Oct 15;408(22):5165-234. doi: 10.1016/j.scitotenv.2010.04.059. Epub 2010 Aug 21.

本文引用的文献

1
Exposure to persistent organic pollutants in Danish pregnant women: Hormone levels and fetal growth indices.丹麦孕妇体内持久性有机污染物的暴露情况：激素水平与胎儿生长指数。
Environ Toxicol Pharmacol. 2023 Apr;99:104108. doi: 10.1016/j.etap.2023.104108. Epub 2023 Mar 13.
2
Systematic review and meta-analysis of epidemiologic data on vaccine response in relation to exposure to five principal perfluoroalkyl substances.系统回顾和荟萃分析流行病学数据，研究疫苗反应与接触五种主要全氟烷基物质的关系。
Environ Int. 2023 Feb;172:107734. doi: 10.1016/j.envint.2023.107734. Epub 2023 Jan 7.
3
Receptor-based in vitro activities to assess human exposure to chemical mixtures and related health impacts.
基于受体的体外活性评估人类接触化学混合物及相关健康影响。
Environ Int. 2021 Jan;146:106191. doi: 10.1016/j.envint.2020.106191. Epub 2020 Oct 14.
4
Exposure to Perflouroalkyl acids and foetal and maternal thyroid status: a review.全氟烷基酸暴露与胎儿和母体甲状腺功能：综述。
Environ Health. 2020 Oct 13;19(1):107. doi: 10.1186/s12940-020-00647-1.
5
Persistent organic pollutants in Greenlandic pregnant women and indices of foetal growth: The ACCEPT study.格陵兰岛孕妇体内的持久性有机污染物与胎儿生长指数：ACCEPT 研究。
Sci Total Environ. 2020 Jan 1;698:134118. doi: 10.1016/j.scitotenv.2019.134118. Epub 2019 Aug 27.
6
Dietary risk factors for inflammatory bowel diseases in a high-risk population: Results from the Faroese IBD study.高风险人群中炎症性肠病的饮食风险因素：法罗群岛 IBD 研究结果。
United European Gastroenterol J. 2019 Aug;7(7):924-932. doi: 10.1177/2050640619852244. Epub 2019 May 19.
7
Cancer Incidence and Mortality in Greenland 1983-2014 - Including Comparison With the Other Nordic Countries.1983 - 2014年格陵兰岛的癌症发病率和死亡率——包括与其他北欧国家的比较。
EClinicalMedicine. 2018 Aug 29;2-3:37-49. doi: 10.1016/j.eclinm.2018.08.003. eCollection 2018 Aug-Sep.
8
Pregnant Inuit Women's Exposure to Metals and Association with Fetal Growth Outcomes: ACCEPT 2010⁻2015.因纽特孕妇的金属暴露及其与胎儿生长结局的关系：ACCEPT 2010⁻2015。
Int J Environ Res Public Health. 2019 Apr 1;16(7):1171. doi: 10.3390/ijerph16071171.
9
Associations of Fetal Growth Outcomes with Measures of the Combined Xenoestrogenic Activity of Maternal Serum Perfluorinated Alkyl Acids in Danish Pregnant Women.胎儿生长结局与丹麦孕妇血清中全氟烷基酸的联合类雌激素活性的测量值之间的关联。
Environ Health Perspect. 2019 Jan;127(1):17006. doi: 10.1289/EHP1884.
10
Prevalence of heart attack and stroke and associated risk factors among Inuit in Canada: A comparison with the general Canadian population.加拿大因纽特人心血管疾病（心脏病和中风）的患病率及其相关风险因素：与加拿大普通人群的比较。
Int J Hyg Environ Health. 2019 Mar;222(2):319-326. doi: 10.1016/j.ijheh.2018.12.003. Epub 2018 Dec 18.