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用于生物医学光学的400至1550纳米硅基体模的开发。

Development of silicone-based phantoms for biomedical optics from 400 to 1550 nm.

作者信息

Wagner Markus, Fugger Oliver, Foschum Florian, Kienle Alwin

机构信息

Institut fuer Lasertechnologien in der Medizin und Meßtechnik an der Universität Ulm, Helmholtzstraße 12, Ulm, Germany.

出版信息

Biomed Opt Express. 2024 Oct 28;15(11):6561-6572. doi: 10.1364/BOE.533481. eCollection 2024 Nov 1.

DOI:10.1364/BOE.533481
PMID:39553884
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11563330/
Abstract

This work describes the development of silicone-based evaluation phantoms for biomedical optics in the wavelength range from 400 to 1550 nm. The absorption coefficient and the reduced scattering coefficient were determined using an integrating sphere setup. Zirconium dioxide pigments were used as scatterers and carbon black as absorbers. We developed an in-house manufacturing process using a Hauschild SpeedMixer to ensure reproducibility. A set of nine cubic phantoms with three different reduced scattering and absorption coefficients was produced. Prediction of the and was done by using the weighted mass concentrations of the used materials. The average prediction accuracy over all wavelengths and phantoms is 1.0% for the reduced scattering coefficient and 3.5% for the absorption coefficient.

摘要

这项工作描述了用于生物医学光学的硅基评估体模在400至1550纳米波长范围内的开发情况。使用积分球装置测定吸收系数和约化散射系数。二氧化锆颜料用作散射体，炭黑用作吸收体。我们开发了一种使用豪施尔德高速混合器的内部制造工艺，以确保可重复性。制作了一组九个具有三种不同约化散射和吸收系数的立方体模。通过使用所用材料的加权质量浓度来预测和。在所有波长和体模上，约化散射系数的平均预测精度为1.0%，吸收系数的平均预测精度为3.5%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/12dfc8c706ee/boe-15-11-6561-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/a468d20420be/boe-15-11-6561-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/512ef4d808e7/boe-15-11-6561-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/e49709737a3b/boe-15-11-6561-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/71f57e152037/boe-15-11-6561-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/fd0733e0b92a/boe-15-11-6561-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/a770dcef6fa3/boe-15-11-6561-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/3e2a7aea9139/boe-15-11-6561-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/d1356f0e3eb6/boe-15-11-6561-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/4f437fb6a753/boe-15-11-6561-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/12dfc8c706ee/boe-15-11-6561-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/a468d20420be/boe-15-11-6561-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/512ef4d808e7/boe-15-11-6561-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/e49709737a3b/boe-15-11-6561-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/71f57e152037/boe-15-11-6561-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/fd0733e0b92a/boe-15-11-6561-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/a770dcef6fa3/boe-15-11-6561-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/3e2a7aea9139/boe-15-11-6561-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/d1356f0e3eb6/boe-15-11-6561-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/4f437fb6a753/boe-15-11-6561-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e7f/11563330/12dfc8c706ee/boe-15-11-6561-g010.jpg

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