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不仅是一种环境细菌,而且是一种潜在的机会性威胁:一例伴有皮肤坏死的骨炎病例报告及文献综述

, not only an environmental bacterium, but a potential opportunistic threat: Case report of an osteitis with skin necrosis and mini review of the literature.

作者信息

Blairon Laurent, Everaert Johnatan, Baillon Bruno, Collignon Sophie, Coenen François, Cupaiolo Roberto, Beukinga Ingrid, Tré-Hardy Marie

机构信息

Department of Laboratory Medicine, Iris Hospitals South, Brussels, Belgium.

Department of Orthopedics, Iris Hospitals South, Brussels, Belgium.

出版信息

New Microbes New Infect. 2024 Nov 2;62:101524. doi: 10.1016/j.nmni.2024.101524. eCollection 2024 Dec.

Abstract

BACKGROUND

, previously known as , is an environmental bacterium rarely associated with human pathologies. Rare case reports mention sepsis, meningitis and implantable defibrillator infection.

CASE PRESENTATION

A 67-year-old female with multiple comorbidities was referred to the emergency room for a comminuted fracture of both right tibial plateaus secondary to a fall and for which she benefited from an external fixator. After removal of the fixator, failure of osteosynthesis and placement of a new fixator, a skin necrosis appeared and a propeller distal anteromedial thigh perforator flap was performed. After 6 weeks, she presented a necrosis of the flap and an osteitis. The bone biopsy was positive with pure . The patient underwent an above-knee amputation, but 6 weeks later the wound was dehiscent and again positive with pure .

CONCLUSIONS

Serious infections due to are uncommon but can occur in immunocompromised patients. This case illustrates the first reported osteitis and skin necrosis due to .

摘要

背景

,以前称为 ,是一种很少与人类病理相关的环境细菌。罕见的病例报告提到败血症、脑膜炎和植入式除颤器感染。

病例介绍

一名患有多种合并症的67岁女性因跌倒导致右胫骨平台双侧粉碎性骨折被转诊至急诊室,并接受了外固定架治疗。在拆除固定架、骨合成失败并放置新的固定架后,出现了皮肤坏死,并进行了股前内侧螺旋桨远端穿支皮瓣手术。6周后,她出现了皮瓣坏死和骨炎。骨活检显示为纯 阳性。患者接受了膝上截肢,但6周后伤口裂开,再次显示为纯 阳性。

结论

由 引起的严重感染并不常见,但可发生在免疫功能低下的患者中。本病例说明了首例报告的由 引起的骨炎和皮肤坏死。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/247f/11570745/ef0bd7d14030/gr1.jpg

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