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一种使用数学建模和深度学习的传染病控制综合框架。

An Integrated Framework for Infectious Disease Control Using Mathematical Modeling and Deep Learning.

作者信息

Salman Mohammed, Das Pradeep Kumar, Mohanty Sanjay Kumar

机构信息

School of Advanced SciencesVellore Institute of Technology Vellore 632014 India.

School of Electronics EngineeringVellore Institute of Technology Vellore 632014 India.

出版信息

IEEE Open J Eng Med Biol. 2024 Sep 9;6:41-53. doi: 10.1109/OJEMB.2024.3455801. eCollection 2025.

DOI:10.1109/OJEMB.2024.3455801
PMID:39564557
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11573407/
Abstract

Infectious diseases are a major global public health concern. Precise modeling and prediction methods are essential to develop effective strategies for disease control. However, data imbalance and the presence of noise and intensity inhomogeneity make disease detection more challenging. In this article, a novel infectious disease pattern prediction system is proposed by integrating deterministic and stochastic model benefits with the benefits of the deep learning model. The combined benefits yield improvement in the performance of solution prediction. Moreover, the objective is also to investigate the influence of time delay on infection rates and rates associated with vaccination. In this proposed framework, at first, the global stability at disease free equilibrium is effectively analysed using Routh-Haurwitz criteria and Lyapunov method, and the endemic equilibrium is analysed using non-linear Volterra integral equations in the infectious disease model. Unlike the existing model, emphasis is given to suggesting a model that is capable of investigating stability while considering the effect of vaccination and migration rate. Next, the influence of vaccination on the rate of infection is effectively predicted using an efficient deep learning model by employing the long-term dependencies in sequential data. Thus making the prediction more accurate.

摘要

传染病是全球主要的公共卫生问题。精确的建模和预测方法对于制定有效的疾病控制策略至关重要。然而,数据不平衡以及噪声和强度不均匀性的存在使得疾病检测更具挑战性。在本文中,通过将确定性和随机模型的优点与深度学习模型的优点相结合,提出了一种新型传染病模式预测系统。这些优点的结合提高了预测解决方案的性能。此外,目标还包括研究时间延迟对感染率和疫苗接种率的影响。在这个提出的框架中,首先,使用劳斯 - 赫尔维茨准则和李雅普诺夫方法有效地分析了无病平衡点的全局稳定性,并在传染病模型中使用非线性沃尔泰拉积分方程分析了地方病平衡点。与现有模型不同,重点在于提出一个能够在考虑疫苗接种和迁移率影响的同时研究稳定性的模型。接下来,通过利用序列数据中的长期依赖性,使用高效的深度学习模型有效地预测了疫苗接种对感染率的影响。从而使预测更加准确。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fc6/11573407/04e73b851f03/mohan1-3455801.jpg
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本文引用的文献

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The role of delay in vaccination rate on Covid-19.疫苗接种延迟对新冠病毒病疫苗接种率的影响。
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The role of vaccination and public awareness in forecasts of Mpox incidence in the United Kingdom.疫苗接种和公众意识在预测英国猴痘发病率中的作用。
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An Efficient Detection and Classification of Acute Leukemia Using Transfer Learning and Orthogonal Softmax Layer-Based Model.基于迁移学习和正交 Softmax 层的急性白血病高效检测与分类方法
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