Department of Health Sciences, University of Florence, Florence, Italy.
Department of Psychiatry and Neuropsychology, Maastricht University, Maastricht, The Netherlands.
Clin Psychol Psychother. 2024 Nov-Dec;31(6):e70022. doi: 10.1002/cpp.70022.
The Mental Pain Questionnaire (MPQ) was developed using a clinimetric approach to bring together the key features of mental pain into a single, brief, transdiagnostic scale. The present study aims at extending the validation of the MPQ to people from three different clinical settings.
A multicentre, cross-sectional study on adults diagnosed with migraine (n = 256), systemic sclerosis (n = 219), or mental disorders (n = 138) was conducted. The MPQ was administered; Rasch and Mokken analyses were performed to assess clinimetric validity.
The overall fit to the Rasch model indicated a misfit, improved by the exclusion of a single item. MPQ showed to be unidimensional. MPQ total score and individual items scalability were optimal except for the same item. The total MPQ score showed an optimal scalability for the systemic sclerosis sample and an acceptable scalability for the migraine and mental disorders samples. Local dependency was found between two pairs of items. Person separation reliability indices (PSI 0.45) showed that the MPQ could not distinguish between groups with different levels of mental pain.
Mental pain has the potential to serve as a truly generic patient-centred outcome measure. Recommendations are made for revisions of the original MPQ, but these will require testing in further validation studies.
精神痛苦问卷(MPQ)是采用临床计量学方法开发的,它将精神痛苦的关键特征整合到一个单一、简短、跨诊断的量表中。本研究旨在将 MPQ 的验证扩展到来自三个不同临床环境的人群。
对患有偏头痛(n=256)、系统性硬化症(n=219)或精神障碍(n=138)的成年人进行了一项多中心、横断面研究。对参与者进行了 MPQ 测试;并进行了 Rasch 和 Mokken 分析,以评估临床有效性。
总体而言,Rasch 模型的拟合度表明存在不匹配,通过排除一个项目得到了改善。MPQ 呈现出单维性。MPQ 总分和各个项目的可度量性是最优的,除了一个项目外。对于系统性硬化症样本,MPQ 总分的可度量性最佳,对于偏头痛和精神障碍样本,可度量性可接受。发现了两个项目对之间的局部依赖性。个体分离可靠性指数(PSI 0.45)表明,MPQ 无法区分具有不同程度精神痛苦的人群。
精神痛苦有可能成为一种真正通用的以患者为中心的结局衡量标准。对原始 MPQ 提出了修订建议,但这需要在进一步的验证研究中进行测试。