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医学中的量子计算。

Quantum Computing in Medicine.

机构信息

Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1X6, Canada.

Department of Radiation Oncology, University of Toronto, Toronto, ON M5T 1P5, Canada.

出版信息

Med Sci (Basel). 2024 Nov 17;12(4):67. doi: 10.3390/medsci12040067.

DOI:10.3390/medsci12040067
PMID:39584917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11586987/
Abstract

Quantum computing (QC) represents a paradigm shift in computational power, offering unique capabilities for addressing complex problems that are infeasible for classical computers. This review paper provides a detailed account of the current state of QC, with a particular focus on its applications within medicine. It explores fundamental concepts such as qubits, superposition, and entanglement, as well as the evolution of QC from theoretical foundations to practical advancements. The paper covers significant milestones where QC has intersected with medical research, including breakthroughs in drug discovery, molecular modeling, genomics, and medical diagnostics. Additionally, key quantum techniques such as quantum algorithms, quantum machine learning (QML), and quantum-enhanced imaging are explained, highlighting their relevance in healthcare. The paper also addresses challenges in the field, including hardware limitations, scalability, and integration within clinical environments. Looking forward, the paper discusses the potential for quantum-classical hybrid systems and emerging innovations in quantum hardware, suggesting how these advancements may accelerate the adoption of QC in medical research and clinical practice. By synthesizing reliable knowledge and presenting it through a comprehensive lens, this paper serves as a valuable reference for researchers interested in the transformative potential of QC in medicine.

摘要

量子计算 (QC) 代表了计算能力的范式转变,为解决传统计算机难以处理的复杂问题提供了独特的能力。本文详细介绍了 QC 的现状,特别关注其在医学中的应用。本文探讨了量子比特、叠加和纠缠等基本概念,以及从理论基础到实际进展的 QC 演变。本文涵盖了 QC 与医学研究交叉的重要里程碑,包括药物发现、分子建模、基因组学和医学诊断方面的突破。此外,还解释了关键的量子技术,如量子算法、量子机器学习 (QML) 和量子增强成像,强调了它们在医疗保健中的相关性。本文还讨论了该领域面临的挑战,包括硬件限制、可扩展性以及在临床环境中的集成。展望未来,本文讨论了量子-经典混合系统和新兴量子硬件创新的潜力,提出了这些进展如何加速 QC 在医学研究和临床实践中的采用。通过综合可靠的知识并通过全面的视角呈现,本文为对 QC 在医学中的变革潜力感兴趣的研究人员提供了有价值的参考。

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本文引用的文献

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Ethical Considerations in Human-Centered AI: Advancing Oncology Chatbots Through Large Language Models.以人类为中心的人工智能中的伦理考量:通过大语言模型推进肿瘤学聊天机器人
JMIR Bioinform Biotechnol. 2024 Nov 6;5:e64406. doi: 10.2196/64406.
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How can quantum computing be applied in clinical trial design and optimization?量子计算如何应用于临床试验设计和优化?
Trends Pharmacol Sci. 2024 Oct;45(10):880-891. doi: 10.1016/j.tips.2024.08.005. Epub 2024 Sep 23.
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Revolutionizing Healthcare: The Emerging Role of Quantum Computing in Enhancing Medical Technology and Treatment.
量子计算在生物医学与医疗保健中的潜在作用:超越人工智能的新前沿
Cureus. 2025 Apr 22;17(4):e82759. doi: 10.7759/cureus.82759. eCollection 2025 Apr.
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A quantum computing approach to beam angle optimization.一种用于射束角度优化的量子计算方法。
ArXiv. 2025 Apr 10:arXiv:2504.07844v1.
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Quantum physics at a historic milestone: How has it shaped medical physics?量子物理学处于历史里程碑:它如何塑造了医学物理学?
Z Med Phys. 2025 May;35(2):123-126. doi: 10.1016/j.zemedi.2025.02.002. Epub 2025 Mar 5.
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Monte Carlo Simulations in Nanomedicine: Advancing Cancer Imaging and Therapy.纳米医学中的蒙特卡洛模拟:推动癌症成像与治疗
Nanomaterials (Basel). 2025 Jan 15;15(2):117. doi: 10.3390/nano15020117.
变革医疗保健:量子计算在提升医疗技术与治疗方面的新兴作用。
Cureus. 2024 Aug 22;16(8):e67486. doi: 10.7759/cureus.67486. eCollection 2024 Aug.
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A novel approach to recognition of Alzheimer's and Parkinson's diseases: random subspace ensemble classifier based on deep hybrid features with a super-resolution image.一种识别阿尔茨海默病和帕金森病的新方法:基于具有超分辨率图像的深度混合特征的随机子空间集成分类器。
PeerJ Comput Sci. 2024 Feb 27;10:e1862. doi: 10.7717/peerj-cs.1862. eCollection 2024.
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The power of quantum neural networks.量子神经网络的力量。
Nat Comput Sci. 2021 Jun;1(6):403-409. doi: 10.1038/s43588-021-00084-1. Epub 2021 Jun 24.
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