视网膜静脉阻塞继发视网膜前膜玻璃体切除术的解剖学、功能及预后结果
Anatomical, Functional, and Prognostic Results of Vitrectomy in Epiretinal Membranes Secondary to Retinal Vein Occlusions.
作者信息
Chung Yoo-Ri, Mainguy Adam, Chatziralli Irini, Smaoui Anissa, Bodaghi Bahram, Paques Michel, Tadayoni Ramin, Cicinelli Maria Vittoria, Touhami Sara
机构信息
Department of Ophthalmology, Pitié-Salpêtrière University Hospital, Sorbonne University, Paris, France.
Department of Ophthalmology, Ajou University School of Medicine, Suwon, Republic of Korea.
出版信息
Ophthalmologica. 2025;248(1):29-39. doi: 10.1159/000542770. Epub 2024 Nov 25.
INTRODUCTION
We investigated the anatomical and functional results of vitrectomy associated with the peeling of secondary epiretinal membranes (ERM) in patients with retinal vein occlusion (RVO) and determined the prognostic factors of surgical outcomes.
METHODS
This retrospective, multicenter, observational study included 50 patients with RVO who underwent vitrectomy with ERM removal between July 2012 and February 2021. Visual acuity (VA) and central macular thickness (CMT) were investigated up to 3 years. Univariate analysis identified the predictive factors associated with functional and anatomical outcomes.
RESULTS
Fifty eyes from 50 patients (62% with central RVO) were included. The mean VA of 0.9 ± 0.7 logMAR preoperatively improved to 0.5 ± 0.5 logMAR after 24 months (p = 0.01). Anatomically, the mean preoperative CMT was 501 ± 168 μm, decreasing to 348 ± 108 μm at month 24 (p = 0.008). By 36 months, VA had improved or stabilized in 90% of the eyes, whereas CMT had been reduced by at least 20% from baseline in 80% of the eyes. A lower number of intravitreal injections (IVI) were required after vitrectomy. Worse preoperative VA, absence of preoperative panretinal photocoagulation, and postoperative use of adjunctive IVI were associated with VA recovery. Higher baseline CMT and the use of preoperative dexamethasone injections were associated with an improvement in CMT.
CONCLUSION
Vitrectomy for ERM secondary to RVO was effective in improving VA and recovering CMT for up to 3 years and reduced the number of IVIs.
INTRODUCTION
We investigated the anatomical and functional results of vitrectomy associated with the peeling of secondary epiretinal membranes (ERM) in patients with retinal vein occlusion (RVO) and determined the prognostic factors of surgical outcomes.
METHODS
This retrospective, multicenter, observational study included 50 patients with RVO who underwent vitrectomy with ERM removal between July 2012 and February 2021. Visual acuity (VA) and central macular thickness (CMT) were investigated up to 3 years. Univariate analysis identified the predictive factors associated with functional and anatomical outcomes.
RESULTS
Fifty eyes from 50 patients (62% with central RVO) were included. The mean VA of 0.9 ± 0.7 logMAR preoperatively improved to 0.5 ± 0.5 logMAR after 24 months (p = 0.01). Anatomically, the mean preoperative CMT was 501 ± 168 μm, decreasing to 348 ± 108 μm at month 24 (p = 0.008). By 36 months, VA had improved or stabilized in 90% of the eyes, whereas CMT had been reduced by at least 20% from baseline in 80% of the eyes. A lower number of intravitreal injections (IVI) were required after vitrectomy. Worse preoperative VA, absence of preoperative panretinal photocoagulation, and postoperative use of adjunctive IVI were associated with VA recovery. Higher baseline CMT and the use of preoperative dexamethasone injections were associated with an improvement in CMT.
CONCLUSION
Vitrectomy for ERM secondary to RVO was effective in improving VA and recovering CMT for up to 3 years and reduced the number of IVIs.
引言
我们研究了视网膜静脉阻塞（RVO）患者行玻璃体切除术联合剥除继发性视网膜前膜（ERM）后的解剖学和功能结果，并确定了手术结果的预后因素。
方法
这项回顾性、多中心、观察性研究纳入了50例在2012年7月至2021年2月期间接受玻璃体切除术联合ERM剥除的RVO患者。对视力（VA）和中心黄斑厚度（CMT）进行了长达3年的研究。单因素分析确定了与功能和解剖学结果相关的预测因素。
结果
纳入了50例患者的50只眼（62%为中心性RVO）。术前平均VA为0.9±0.7 logMAR，24个月后改善至0.5±0.5 logMAR（p = 0.01）。在解剖学上，术前平均CMT为501±168μm，在第24个月时降至348±108μm（p = 0.008）。到36个月时，90%的眼睛VA得到改善或稳定，而80%的眼睛CMT较基线水平降低了至少20%。玻璃体切除术后所需的玻璃体内注射（IVI）次数减少。术前VA较差、术前未行全视网膜光凝以及术后使用辅助性IVI与VA恢复相关。基线CMT较高和术前使用地塞米松注射与CMT改善相关。
结论
RVO继发ERM的玻璃体切除术在改善VA和恢复CMT方面有效，长达3年，并减少了IVI的次数。
引言
我们研究了视网膜静脉阻塞（RVO）患者行玻璃体切除术联合剥除继发性视网膜前膜（ERM）后的解剖学和功能结果，并确定了手术结果的预后因素。
方法
这项回顾性、多中心、观察性研究纳入了50例在2012年7月至2021年2月期间接受玻璃体切除术联合ERM剥除的RVO患者。对视力（VA）和中心黄斑厚度（CMT）进行了长达3年的研究。单因素分析确定了与功能和解剖学结果相关的预测因素。
结果
纳入了50例患者的50只眼（62%为中心性RVO）。术前平均VA为0.9±0.7 logMAR，24个月后改善至0.5±0.5 logMAR（p = 0.01）。在解剖学上，术前平均CMT为501±168μm，在第24个月时降至348±108μm（p = 0.008）。到36个月时，90%的眼睛VA得到改善或稳定，而80%的眼睛CMT较基线水平降低了至少20%。玻璃体切除术后所需的玻璃体内注射（IVI）次数减少。术前VA较差、术前未行全视网膜光凝以及术后使用辅助性IVI与VA恢复相关。基线CMT较高和术前使用地塞米松注射与CMT改善相关。
结论
RVO继发ERM的玻璃体切除术在改善VA和恢复CMT方面有效，长达3年，并减少了IVI的次数。
Zotero 插件