Faculty of Medicine and Health Science, University Malaysia Sabah, Kota Kinabalu, Malaysia.
Orthopedics Ward 2, Yunnan Cancer Hospital, Kunming, China.
Hum Vaccin Immunother. 2024 Dec 31;20(1):2429237. doi: 10.1080/21645515.2024.2429237. Epub 2024 Nov 26.
Immunotherapy has emerged as a crucial advancement in pulmonary carcinoma treatment. Nevertheless, its unique side effects not only reduce patients' quality of life but also affect treatment efficacy, with severe cases potentially endangering the patient's life. This study uses bibliometric analysis to perform a comprehensive bibliometric analysis literature on IRAEs in lung cancer from 1991 to 2023, retrieved from the Web of Science database. The dataset was analyzed using VOSviewer and CiteSpace to identify trends, key contributors, and emerging research areas. A total of 124 publications were analyzed, revealing a notable increase in research activity post-2015, with China and the USA contributing over 50% of the studies. This research highlights the importance of understanding IRAEs and suggests future investigations into the pulmonary microbiota and tumor microenvironment.
免疫疗法已成为治疗肺癌的重要进展。然而，它独特的副作用不仅降低了患者的生活质量，还影响了治疗效果，严重的情况下可能危及患者的生命。本研究采用文献计量分析方法，对 1991 年至 2023 年从 Web of Science 数据库中检索到的肺癌 IRAE 进行了全面的文献计量分析。使用 VOSviewer 和 CiteSpace 对数据集进行分析，以确定趋势、主要贡献者和新兴研究领域。共分析了 124 篇出版物，显示出 2015 年后研究活动的显著增加，中国和美国贡献了超过 50%的研究。这项研究强调了了解 IRAE 的重要性，并建议未来对肺部微生物群和肿瘤微环境进行研究。
