Department of Biology, Faculty of Life Sciences, University of Okara, Okara, 56130, Pakistan.
Department of Zoology, Faculty of Life Sciences, University of Okara, Okara, 56130, Pakistan.
Neurogenetics. 2024 Nov 26;26(1):10. doi: 10.1007/s10048-024-00791-7.
This review article investigates the intricate relationship between nutrigenomics and neurological disorders, highlighting how genetic variations affect an individual's response to nutrients. The study delves into the role of diet-related oxidative stress and the gut-brain axis in the progression and management of brain disorders such as Parkinson's disease, Alzheimer's disease, epilepsy, stroke, migraines, and depression. The review encompasses various clinical trials and introduces new trends and techniques, including omics and artificial intelligence, in identifying and managing neurological disorders. The main findings emphasize that personalized diet recommendations, tailored to an individual's genetic makeup, can significantly improve cognitive health and manage neurological conditions. The study concludes that further research in the field of nutrigenomics is essential to advancing personalized nutrition strategies for better neurological functioning, ultimately linking diet, genes, and brain health.
这篇综述文章探讨了营养基因组学与神经紊乱之间错综复杂的关系，强调了遗传变异如何影响个体对营养物质的反应。该研究深入探讨了与饮食相关的氧化应激和肠脑轴在帕金森病、阿尔茨海默病、癫痫、中风、偏头痛和抑郁症等脑部疾病的发生和管理中的作用。本综述涵盖了各种临床试验，并介绍了新的趋势和技术，包括组学和人工智能，以识别和管理神经紊乱。主要研究结果强调，针对个体基因构成的个性化饮食建议可以显著改善认知健康并管理神经紊乱。研究得出的结论是，营养基因组学领域的进一步研究对于推进个性化营养策略以促进更好的神经功能至关重要，最终将饮食、基因和大脑健康联系起来。
