Zhang Zhengyi, Yang Meijie, Zhou Tong, Chen Yingjie, Zhou Xiujuan, Long Kunlan
School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Department of Critical Care Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Front Med (Lausanne). 2024 Nov 13;11:1510463. doi: 10.3389/fmed.2024.1510463. eCollection 2024.
The association between the gut microbiota and sepsis has garnered attention in the field of intestinal research in sepsis. This study utilizes bibliometric methods to visualize and analyze the literature on gut microbiota research in sepsis from 2011 to 2024, providing a scientific foundation for research directions and key issues in this domain.
Original articles and reviews of gut microbiota research in sepsis, which published in English between 2011 and 2024, were obtained from the Web of Science Core Collection on June 21, 2024. Python, VOSviewer, and CiteSpace software were used for the visual analysis of the retrieved data.
A total of 1,031 articles were analyzed, originating from 72 countries or regions, 1,614 research institutions, and 6,541 authors. The articles were published in 434 different journals, covering 89 different research fields. The number of publications and citations in this research area showed a significant growth trend from 2011 to 2024, with China, the United States, and the United Kingdom being the main research forces. Asada Leelahavanichkul from Thailand was identified as the most prolific author, making him the most authoritative expert in this field. "Nutrients" had the highest number of publications, while "Frontiers in Cellular and Infection Microbiology," "Frontiers in Immunology" and "the International Journal of Molecular Sciences" have shown increasing attention to this field in the past 2 years. Author keywords appearing more than 100 times included "gut microbiota (GM)," "sepsis" and "microbiota." Finally, this study identified "lipopolysaccharides (LPS)," "short-chain fatty acids (SCFAs)," "probiotics," "fecal microbiota transplantation (FMT)" and "gut-liver axis" as the research hotspots and potential frontier directions in this field.
This bibliometric study summarizes current important perspectives and offers comprehensive guidance between sepsis and intestinal microbiota, which may help researchers choose the most appropriate research directions.
肠道微生物群与脓毒症之间的关联在脓毒症肠道研究领域引起了关注。本研究运用文献计量学方法，对2011年至2024年脓毒症肠道微生物群研究的文献进行可视化和分析，为该领域的研究方向和关键问题提供科学依据。
于2024年6月21日从科学网核心合集获取2011年至2024年期间以英文发表的脓毒症肠道微生物群研究的原创文章和综述。使用Python、VOSviewer和CiteSpace软件对检索到的数据进行可视化分析。
共分析了1031篇文章，这些文章来自72个国家或地区、1614个研究机构以及6541位作者。文章发表在434种不同的期刊上，涵盖89个不同的研究领域。该研究领域的出版物数量和被引频次从2011年到2024年呈显著增长趋势，中国、美国和英国是主要研究力量。来自泰国的浅田利拉瓦尼奇库尔被确定为发文量最多的作者，使其成为该领域最具权威性的专家。“营养素”的出版物数量最多，而“细胞与感染微生物学前沿”“免疫学前沿”和“国际分子科学杂志”在过去两年对该领域的关注度不断提高。出现次数超过100次的作者关键词包括“肠道微生物群（GM）”“脓毒症”和“微生物群”。最后，本研究确定“脂多糖（LPS）”“短链脂肪酸（SCFAs）”“益生菌”“粪便微生物群移植（FMT）”和“肠 - 肝轴”为该领域的研究热点和潜在前沿方向。
这项文献计量学研究总结了当前的重要观点，并为脓毒症和肠道微生物群之间的研究提供了全面指导，这可能有助于研究人员选择最合适的研究方向。
