Lucas-Domínguez Rut, Vidal-Infer Antonio, Alonso-Arroyo Adolfo, Tarazona-Álvarez Beatriz, Bolaños-Pizarro Máxima, Paredes-Gallardo Vanessa
Department of History of Science and Information Science, University of Valencia, Valencia, Spain; UISYS, Joint Research Unit, University of Valencia, Valencia, Spain. Associated Unit Research Institute for Higher Education and Science (INAECU) UC3M-UAM, Spain; CIBERONC, Valencia, Spain.
Department of History of Science and Information Science, University of Valencia, Valencia, Spain; UISYS, Joint Research Unit, University of Valencia, Valencia, Spain. Associated Unit Research Institute for Higher Education and Science (INAECU) UC3M-UAM, Spain.
Gac Sanit. 2024;38:102432. doi: 10.1016/j.gaceta.2024.102432. Epub 2024 Nov 27.
Understanding and targeting cancer stem cells (CSC) are areas of active research in oncology and further dissemination of scientific results is urgently needed to accelerate the comprehension of their involvement in tumor heterogeneity, resistance to conventional therapies and metastasis. In the context of open science, open access and data sharing, the aim of this study is to assess the current practices of cancer researchers in terms of publications and dissemination of research data.
A bibliometric study was conducted based on a bibliographic search using the Web of Science, and CSC articles with at least one Spanish affiliation were retrieved. A comparative study of the openness criteria of the journals was carried out, as well as an analysis of the associated data attached to the articles as supplementary material or deposited in repositories.
708 documents from 282 journals were retrieved. 303 articles contained associated research data, mostly published in Q1 journals, demonstrating a correlation between impact journals and their commitment to quality improvement. Supplementary material was the preferred method of data sharing, being pdf the most used file type. Only 69 articles mentioned datasets deposited in repositories, mainly from genomic nature. The main cancers studied were digestive and gastrointestinal, neurological, breast, hematological and respiratory, which coincided with the tumor types with the highest incidence and mortality, and in which the presence of CSC has been described.
Researchers and publishers have become more aware of open science practices, but there is still a need for data quality according to the FAIR principles.
了解和靶向癌症干细胞（CSC）是肿瘤学领域的活跃研究方向，迫切需要进一步传播科学成果，以加速对其在肿瘤异质性、对传统疗法的抗性和转移中所起作用的理解。在开放科学、开放获取和数据共享的背景下，本研究旨在评估癌症研究人员在出版物和研究数据传播方面的当前做法。
基于使用科学网进行的文献检索开展了一项文献计量学研究，检索了至少有一个西班牙机构参与的CSC相关文章。对期刊的开放标准进行了比较研究，并对作为补充材料附加到文章或存放在知识库中的相关数据进行了分析。
从282种期刊中检索到708篇文献。303篇文章包含相关研究数据，大多发表在Q1区期刊上，表明高影响力期刊与其对质量提升的承诺之间存在相关性。补充材料是数据共享的首选方式，最常用的文件类型是pdf。只有69篇文章提到了存放在知识库中的数据集，主要是基因组性质的。研究的主要癌症类型为消化和胃肠道、神经、乳腺、血液和呼吸方面的癌症，这些与发病率和死亡率最高的肿瘤类型相符，且其中已描述了CSC的存在。
研究人员和出版商对开放科学实践的认识有所提高，但仍需要根据FAIR原则保证数据质量。
