Department of Translational Medical Science, University of Naples "Federico II", Naples, Italy.
Pediatric Infectious Disease Unit, Department of Maternal and Child health, University Hospital "Federico II", Naples, Italy.
Euro Surveill. 2024 Nov;29(48). doi: 10.2807/1560-7917.ES.2024.29.48.2400746.
Acute myocarditis has risen among paediatric patients in Italy, with 65 clinically suspected cases reported by 12 centres in 2024, 32 linked to parvovirus B19 (B19V) infection. In 11 cases, B19V was not ruled out despite a concurrent European outbreak. Twenty-nine children required intensive care; eight fatalities occurred. While effective for both severe B19V infection and myocarditis, intravenous immunoglobulins were given in only one-third of cases. These findings highlight the need for timely diagnosis, stronger surveillance, and standardised treatment protocols.
意大利儿科患者中急性心肌炎的发病率上升,2024 年 12 个中心报告了 65 例临床疑似病例,其中 32 例与细小病毒 B19(B19V)感染有关。在 11 例病例中,尽管同时发生了欧洲疫情,但仍不能排除 B19V 的可能性。29 例患儿需要重症监护;有 8 例死亡。静脉注射免疫球蛋白虽然对严重 B19V 感染和心肌炎都有效,但仅在三分之一的病例中使用。这些发现强调了及时诊断、加强监测和标准化治疗方案的必要性。