Department of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida, Gainesville.
Department of Clinical Pharmacy and Pharmacy Practice, College of Pharmacy, Yarmouk University, Irbid, Jordan.
J Manag Care Spec Pharm. 2024 Dec;30(12):1355-1363. doi: 10.18553/jmcp.2024.30.12.1355.
In 2021, Medicare Part D gross prescription drug spending amounted to $216 billion, a number that has more than doubled over the last 10 years. Spending in Medicare Part D is concentrated on a small number of drugs, and spending on specialty drugs has increased in recent years. However, the extent to which concentration in Part D spending has changed over time and the drivers of this change have not been described.
To quantify the time trends in Medicare Part D spending and utilization, the concentration of spending, and the share of spending accounted for by specialty drugs from 2012 to 2021.
In this repeated cross-sectional study, we used data from the Centers for Medicare & Medicaid Services Part D Drug Spending Dashboard to investigate the time trends in total gross spending, prescriptions claims, and the average cost of a prescription claim for Part D drugs. We assessed the concentration based on the share of total gross spending and prescriptions by the drugs with the top 1%, 5%, and 10% of the highest spending and Lorenz curves and Gini coefficients. In addition, we stratified our analyses by specialty and nonspecialty drugs.
Over the last 10 years, total gross drug spending in Medicare Part D increased by 103.5%, with a compounded annual growth rate of 8.2%. This change was driven by both increases in prescription claims and price increases of existing drugs to a similar degree. The concentration of spending intensified, with the top 1% of drugs accounting for an escalating share of total spending (from 31.4% to 41.1%). Over the 10-year study period, these top-spending drugs accounted for 5.6% of prescriptions but 34.6% of spending. Lorenz curves and increased Gini coefficients similarly showed that a smaller number of drugs accounted for increased spending over the study period. Specialty drug spending increased by 566.5%, with a compounded annual growth rate of 23.5%. The share of total spending on specialty drugs increased from 21.7% in 2012 to 71.1% in 2021. In 2021, specialty drugs accounted for 6.2% of prescriptions but 71.1% of total spending.
Medicare Part D gross drug spending became increasingly more concentrated from 2012 to 2021, which was especially pronounced for specialty drugs. Increases in prices for specialty and other brand-name drugs will likely continue to drive gross spending upward. Although the Inflation Reduction Act provisions will likely reduce net spending on selected drugs, other policy changes may be warranted.
2021 年,医疗保险处方药总支出达 2160 亿美元,这一数字在过去 10 年中翻了一番还不止。医疗保险处方药支出集中在少数几种药品上,近年来,专科药品支出有所增加。然而,医疗保险处方药支出的集中程度随时间发生了怎样的变化,以及造成这种变化的原因尚不清楚。
从 2012 年到 2021 年,定量描述医疗保险处方药支出和使用、支出集中程度以及专科药品支出占比的时间趋势。
在这项重复横断面研究中,我们使用医疗保险和医疗补助服务中心(Centers for Medicare & Medicaid Services)处方药物支出数据仪表板的数据,研究了医疗保险处方药总支出、处方数量以及处方药单张处方平均费用的时间趋势。我们基于药物支出前 1%、前 5%和前 10%药品的总支出和处方占比,以及洛伦兹曲线和基尼系数,评估了支出的集中程度。此外,我们按专科药品和非专科药品对分析进行了分层。
在过去 10 年中,医疗保险处方药总支出增长了 103.5%,复合年增长率为 8.2%。这种变化是由处方数量增加和现有药物价格上涨共同推动的。支出的集中程度加剧,支出前 1%的药品占总支出的比例不断上升(从 31.4%上升至 41.1%)。在 10 年的研究期间,这些高支出药品仅占处方的 5.6%,但占支出的 34.6%。洛伦兹曲线和基尼系数的增加也表明,在研究期间,少数几种药物的支出占比不断增加。专科药品支出增长了 566.5%,复合年增长率为 23.5%。专科药品支出占总支出的比例从 2012 年的 21.7%上升至 2021 年的 71.1%。2021 年,专科药品占处方的 6.2%,但占总支出的 71.1%。
从 2012 年到 2021 年,医疗保险处方药总支出的集中程度越来越高,专科药品尤其明显。专科药品和其他品牌药品价格的上涨可能会继续推动总支出的增加。虽然《降低通胀法案》(Inflation Reduction Act)的规定可能会降低选定药物的净支出,但可能需要进行其他政策调整。