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热塑性面罩和气动腹部压迫装置在脊柱转移瘤立体定向消融放疗中用于固定的疗效

Efficacy of a thermoplastic mask and pneumatic abdominal compression device for immobilization in stereotactic ablative radiotherapy of spine metastases.

作者信息

Walter Yohan A, Speir Daniel B, Burrell William E, Wang Chiachien J, Wu Hsinshun T

机构信息

Department of Radiation Oncology, Willis Knighton Cancer Center, Shreveport, Louisiana, USA.

出版信息

J Appl Clin Med Phys. 2025 Apr;26(4):e14577. doi: 10.1002/acm2.14577. Epub 2024 Dec 1.

Abstract

Stereotactic ablative radiotherapy (SABR) has become a key technique in management of spine metastases. With improved control over treatment plan dosimetry, there is a greater need for accurate patient positioning to guarantee agreement between the treatment plan and delivered dose. With serious potential complications such as fracture and myelopathy, the margins of error in SABR of the spine are minimal. In this study, we assessed the performance of two patient immobilization setups in SABR for spinal metastases. First, a Type-S head and shoulders mask (CQ Medical, Avondale, PA), and second, the BPL1 setup, which includes a wing board, vacuum bag, and the Respiratory Belt for the Body Pro-Lok ONE (CQ Medical, Avondale, PA). Immobilization was assessed using image-guided intrafraction repositioning shifts. Required planning target volume (PTV) margins were calculated based on repositioning data for 172 treated fractions using 2 standard deviation (2SD) and analytic approaches. Overall, 91.7% and 74.1% of fractions treated had total 3D repositioning shifts ≤3.0  mm using the Type-S and BPL1 setups, respectively. In the thoracic spine, 43.2% and 46.5% of fractions had shifts ≤1.5  mm for the respective setups. Suggested margins were under 3.5  mm in all directions and use cases. In the posterior-anterior direction, the BPL1 setup had a 0.6  mm smaller suggested margin for the thoracic spine compared to the Type-S setup, at 1.4  mm, calculated using the analytic approach. Both the Type-S and BPL1 setups are effective for immobilization in spine SABR. The Type-S demonstrated superior immobilization in the upper spine and remains the clinical standard for cervical and upper thoracic spine positioning. The BPL1 setup showed effective immobilization in use cases treating the mid-to lower thoracic spine and lumbar spine and remains our clinical standard for those use cases. Results additionally demonstrate feasibility of potential PTV margin reduction.

摘要

立体定向消融放疗(SABR)已成为脊柱转移瘤治疗的一项关键技术。随着对治疗计划剂量测定的控制得到改善,对精确的患者定位有了更大需求,以确保治疗计划与实际给予剂量之间的一致性。由于存在骨折和脊髓病等严重潜在并发症,脊柱SABR的误差 margins 极小。在本研究中,我们评估了两种患者固定装置在脊柱转移瘤SABR中的性能。第一种是S型头肩面罩(CQ Medical,宾夕法尼亚州阿冯代尔),第二种是BPL1装置,它包括一个翼板、真空袋和用于Body Pro-Lok ONE的呼吸带(CQ Medical,宾夕法尼亚州阿冯代尔)。使用图像引导的分次内重新定位偏移来评估固定情况。根据172个治疗分次的重新定位数据,采用2标准差(2SD)和分析方法计算所需的计划靶区(PTV) margins 。总体而言,分别使用S型和BPL1装置治疗的分次中,91.7%和74.1%的总三维重新定位偏移≤3.0毫米。在胸椎,相应装置的分次中分别有43.2%和46.5%的偏移≤1.5毫米。在所有方向和应用病例中,建议的 margins 均低于3.5毫米。在前后方向上,使用分析方法计算得出,BPL1装置在胸椎的建议 margin 比S型装置小0.6毫米,为1.4毫米。S型和BPL1装置在脊柱SABR中均能有效固定。S型在脊柱上部显示出更好的固定效果,仍然是颈椎和上胸椎定位的临床标准。BPL1装置在治疗中下段胸椎和腰椎的应用病例中显示出有效的固定效果,仍然是这些应用病例的临床标准。结果还证明了潜在的PTV margin减小的可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a20e/11969103/ace5c31f7437/ACM2-26-e14577-g001.jpg

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