Busey Blake, Estrada Paul, Anwer Javaria
Valley View Health Center, Centralia, WA, USA.
Department of Medicine, Gastroenterology and Advanced Endoscopy, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, TX, USA.
J Family Community Med. 2024 Oct-Dec;31(4):351-354. doi: 10.4103/jfcm.jfcm_143_24. Epub 2024 Oct 10.
Immunoglobulin G4-related disease (IgG4-RD) is a localized or diffuse autoimmune fibro-inflammatory condition that can affect any organ. The literature is sparse on IgG4-RD in the Latino population. This is a case report of a Latino male diagnosed with IgG4-related pancreatitis presenting as a mass. Our 40-year-old Latino male patient presented with diarrhea and epigastric discomfort progressing to jaundice and pruritus. He had associated elevations in liver enzymes, antinuclear antibody, and IgG4. Magnetic resonance cholangiopancreatography revealed a lobulated pancreatic head mass with common bile duct (CBD) narrowing. Endoscopic ultrasound-guided biopsy of the pancreas revealed no malignancy, and the patient underwent CBD stenting through endoscopic retrograde cholangiopancreatography. The patient demonstrated a favorable response to systemic glucocorticoid therapy with resolution of his symptoms and normalization of his liver function tests. Coronavirus disease-2019 infection during treatment had no impact on the outcomes.
免疫球蛋白G4相关性疾病（IgG4-RD）是一种可影响任何器官的局限性或弥漫性自身免疫性纤维炎症性疾病。关于拉丁裔人群中IgG4-RD的文献较少。这是一例被诊断为IgG4相关性胰腺炎并表现为肿块的拉丁裔男性病例报告。我们40岁的拉丁裔男性患者最初出现腹泻和上腹部不适，随后发展为黄疸和瘙痒。他还伴有肝酶、抗核抗体和IgG4升高。磁共振胰胆管造影显示胰头有分叶状肿块，伴胆总管（CBD）狭窄。胰腺的内镜超声引导活检未发现恶性肿瘤，患者通过内镜逆行胰胆管造影接受了CBD支架置入术。患者对全身糖皮质激素治疗反应良好，症状缓解，肝功能检查恢复正常。治疗期间的新型冠状病毒肺炎感染对治疗结果没有影响。
