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韩国弓形虫病患者的临床特征：一项利用健康保险审查与评估服务数据及电子病历的回顾性研究。

Clinical characteristics of toxoplasmosis patients in Korea: A retrospective study using health insurance review and assessment service data and electronic medical records.

作者信息

Ham Do-Won, Jung Bong-Kwang, Shin Ji-Hun, Kim Yong Joon, Seo Kyoung Yul, Lee Seung Mi, Im Jae Hyoung, Kwon Jeong-Ran, Lee Ho-Sung, Hwang Kyung-Won, Shin Eun-Hee

机构信息

Department of Tropical Medicine and Parasitology, Seoul National University College of Medicine, and Institute of Endemic Diseases, Seoul 03080, Korea.

MediCheck Research Institute, Korea Association of Health Promotion, Seoul 07649, Korea.

出版信息

Parasites Hosts Dis. 2024 Nov;62(4):424-437. doi: 10.3347/PHD.24001. Epub 2024 Nov 22.

DOI:10.3347/PHD.24001
PMID:39622654
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11614488/
Abstract

This study aimed to elucidate the clinical characteristics of patients diagnosed with toxoplasmosis in Korea. We collected and analyzed the specific research data of 5,917 patients from the Health Insurance Review and Assessment (HIRA; 2007-2020) and 533 electronic medical records (EMRs; 2003-2021) of Korean patients. The HIRA data showed that toxoplasmosis is an endemic disease that occurs constantly in Korea, with a large proportion of patients complaining of ocular symptoms. Of the 533 patients for whom EMR data were available, 54.6% were diagnosed with toxoplasmosis; ocular toxoplasmosis (35.7%), congenital toxoplasmosis (4.7%), cerebral toxoplasmosis (4.1%), pulmonary toxoplasmosis (0.4%), and toxoplasma hepatitis (0.6%), in order of frequency. In ocular cases, 54.4% of the patients had diverse ocular pathologies. Toxoplasmosis in Korea is characterized by a high frequency of ocular symptoms, most patients are adults, and 51.8% of patients with seropositivity were positive for IgG, suggesting prior infection. This study highlights that patients with ocular symptoms are included in the major diagnosis group for acquired toxoplasmosis in Korea.

摘要

本研究旨在阐明韩国确诊弓形虫病患者的临床特征。我们收集并分析了来自韩国健康保险审查与评估机构（HIRA；2007 - 2020年）的5917例患者以及533例韩国患者电子病历（EMR；2003 - 2021年）的特定研究数据。HIRA数据显示，弓形虫病在韩国是一种地方性疾病，经常发生，很大一部分患者抱怨有眼部症状。在可获取EMR数据的533例患者中，54.6%被诊断为弓形虫病；按频率依次为眼部弓形虫病（35.7%）、先天性弓形虫病（4.7%）、脑弓形虫病（4.1%）、肺弓形虫病（0.4%）和弓形虫性肝炎（0.6%）。在眼部病例中，54.4%的患者有多种眼部病变。韩国的弓形虫病特点是眼部症状出现频率高，大多数患者为成年人，51.8%的血清阳性患者IgG呈阳性，提示既往感染。本研究强调，有眼部症状的患者被纳入韩国获得性弓形虫病的主要诊断组。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0503/11614488/1ef507effb41/phd-24001f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0503/11614488/44fd09b0fd0a/phd-24001f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0503/11614488/197ea6103174/phd-24001f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0503/11614488/1367e7c94bb6/phd-24001f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0503/11614488/1ef507effb41/phd-24001f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0503/11614488/44fd09b0fd0a/phd-24001f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0503/11614488/197ea6103174/phd-24001f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0503/11614488/1367e7c94bb6/phd-24001f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0503/11614488/1ef507effb41/phd-24001f4.jpg

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本文引用的文献

1
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BMC Womens Health. 2023 Aug 10;23(1):425. doi: 10.1186/s12905-023-02560-4.
2
exposure in Brazilian indigenous populations, their dogs, environment, and healthcare professionals.巴西原住民、他们的狗、环境以及医护人员中的暴露情况。
One Health. 2023 May 18;16:100567. doi: 10.1016/j.onehlt.2023.100567. eCollection 2023 Jun.
3
Ocular Toxoplasmosis.
眼弓形虫病。
Ocul Immunol Inflamm. 2023 Sep;31(7):1342-1361. doi: 10.1080/09273948.2022.2117705. Epub 2022 Sep 12.
4
Toxoplasma gondii in humans and animals in Japan: An epidemiological overview.日本人类和动物中的弓形虫：流行病学概述。
Parasitol Int. 2022 Apr;87:102533. doi: 10.1016/j.parint.2021.102533. Epub 2021 Dec 27.
5
Toxoplasma gondii in South America: a differentiated pattern of spread, population structure and clinical manifestations.南美洲的刚地弓形虫：传播方式、种群结构和临床表现的差异模式。
Parasitol Res. 2021 Sep;120(9):3065-3076. doi: 10.1007/s00436-021-07282-w. Epub 2021 Aug 14.
6
Retrospective studies - utility and caveats.回顾性研究——实用性及注意事项。
J R Coll Physicians Edinb. 2020 Dec;50(4):398-402. doi: 10.4997/JRCPE.2020.409.
7
Seronegative ocular toxoplasma panuveitis in an immunocompetent patient.免疫功能正常患者的血清阴性眼弓形虫全葡萄膜炎。
Am J Ophthalmol Case Rep. 2020 May 15;19:100745. doi: 10.1016/j.ajoc.2020.100745. eCollection 2020 Sep.
8
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J Clin Microbiol. 2020 Aug 24;58(9). doi: 10.1128/JCM.00505-20.
9
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Rev Soc Bras Med Trop. 2019 Apr 11;52:e20180228. doi: 10.1590/0037-8682-0228-2018.
10
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Korean J Pediatr. 2018 Apr;61(4):114-120. doi: 10.3345/kjp.2018.61.4.114. Epub 2018 Apr 23.