Almasoud Yaser, Alwelaie Manar, Aldosari Zeyad, Alotaibi Sarah, Alsayari Abdullah, Alzyadi Ghada, Almutairi Mohammed, Alajel Sulaiman, Tamim Abdullah Al, Alharbi Hibah
Saudi Food and Drug Authority, Riyadh 0112038222, Saudi Arabia.
Toxicol Rep. 2024 Nov 9;13:101787. doi: 10.1016/j.toxrep.2024.101787. eCollection 2024 Dec.
Milk is susceptible to Aflatoxin M1 (AFM1) contamination, mainly through consumption of contaminated animal's feed. The natural occurrence of aflatoxin M1 (AFB1) has been surveyed in samples of milk and milk powder. Samples collected from different regions of Saudi Arabia during the period from 2013 to 2021 were subjected to high-performance liquid chromatography analysis, and (AFB1) was quantified with detection limits of 0.5 µg/kg. The Saudi Food and Drug Authority has taken strong actions to limit AFM1 contamination, increase aflatoxin control, and modify the regulations. A study analyzed 363 randomly collected milk samples (168 milk, 195 milk powder) from Saudi Arabia using LC-MS/MS. Out of the 363 samples, 20 were positive for AFM1, with 343 were within the limits. One out of the 168 milk samples and 19 out of the 195 milk powder samples exceeded the limits, with seven originating from Saudi Arabia. The highest AFM1 concentration (3.97 µg/kg) was found in the Saudi samples. Saudi Arabia's mycotoxin regulations significantly reduced AFM1 contamination in milk, which is not considered a serious health hazard.
牛奶易受黄曲霉毒素M1（AFM1）污染，主要是通过食用受污染的动物饲料。已对牛奶和奶粉样本中的黄曲霉毒素M1（AFB1）天然存在情况进行了调查。对2013年至2021年期间从沙特阿拉伯不同地区采集的样本进行了高效液相色谱分析，AFB1的定量检测限为0.5µg/kg。沙特食品药品管理局已采取有力行动来限制AFM1污染、加强黄曲霉毒素管控并修订相关法规。一项研究使用液相色谱-串联质谱法分析了从沙特阿拉伯随机采集的363份牛奶样本（168份牛奶、195份奶粉）。在这363份样本中，20份AFM1呈阳性，343份在限值范围内。168份牛奶样本中有1份、195份奶粉样本中有19份超过限值，其中7份来自沙特阿拉伯。在沙特样本中发现了最高的AFM1浓度（3.97µg/kg）。沙特阿拉伯的霉菌毒素法规显著降低了牛奶中的AFM1污染，牛奶不被视为严重的健康危害。
