Wood Erin E, Liang Yuanyuan, Moon Tae-Joon, Hill-Kapturczak Nathalie, Wasserman Alexander M, Roache John D, Mathias Charles W, Blumenthal Heidemarie, Dougherty Donald M
Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Department of Psychology, University of Illinois Urbana-Champaign, Champaign, Illinois, USA.
Subst Use Misuse. 2025;60(3):403-413. doi: 10.1080/10826084.2024.2434007. Epub 2024 Dec 3.
The social and local-home environment impacts youth's likelihood of early substance use initiation (SUI). Yet, it is unknown whether protective or risk factors are salient for all forms of youth SUI, or may be specific to certain substances (e.g., alcohol, cannabis). Additionally, certain family factors - such as having a family history of SUD (FH+)-may exacerbate risk for and mitigate protection from alcohol (AUI) and cannabis (CUI) use initiation.
Using a longitudinal cohort of 387 adolescents, we aimed to understand how the link between social and local-home factors on AUI and CUI was moderated by FH status.
Results indicated that affiliating with risky peers significantly increased the risk of AUI and CUI, but that this relationship was not moderated by FH status. On the other hand, the link between mother-youth relationship quality and CUI, was potentially moderated by FH status such that being FH+ attenuated the protective effect of a positive relationship with parents on SUI.
This research could provide evidence that youth who are at risk of early SUI, particularly those who are FH+, may benefit from programs designed to reduce affiliation with risky peers.
社会和家庭环境会影响青少年早期开始使用毒品(SUI)的可能性。然而,尚不清楚保护因素或风险因素对于所有形式的青少年SUI是否显著,或者是否可能特定于某些毒品(例如酒精、大麻)。此外,某些家庭因素——如有药物使用障碍家族史(FH+)——可能会加剧酒精使用障碍(AUI)和大麻使用障碍(CUI)开始的风险,并削弱对其的保护作用。
通过对387名青少年的纵向队列研究,我们旨在了解FH状态如何调节社会和家庭因素与AUI和CUI之间的联系。
结果表明,与有风险的同龄人交往会显著增加AUI和CUI的风险,但这种关系不受FH状态的调节。另一方面,母子关系质量与CUI之间的联系可能受FH状态的调节,即FH+会削弱与父母的积极关系对SUI的保护作用。
本研究可以提供证据表明,有早期SUI风险的青少年,尤其是那些FH+的青少年,可能会从旨在减少与有风险的同龄人交往的项目中受益。