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一例三重呼吸道合并感染病例:新型冠状病毒肺炎、肠道病毒和副流感病毒

A Case of Triple Respiratory Coinfection: COVID-19, Enterovirus, and Parainfluenza.

作者信息

Bangash Muhammad H, Awais Shehar B, Cheema Chaudhary A, Luker Andrew J, Prado Steven, Waheed Abdul

机构信息

Department of Family Medicine, WellSpan Good Samaritan Hospital, Family Medicine Residency Program, Lebanon, USA.

Department of Family Medicine, Creighton University, School of Medicine, Phoenix, USA.

出版信息

Cureus. 2024 Nov 3;16(11):e72949. doi: 10.7759/cureus.72949. eCollection 2024 Nov.

DOI:10.7759/cureus.72949
PMID:39634984
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11615252/
Abstract

We report a case of a 34-year-old female who presented to the emergency department with fever, nausea, vomiting, and diarrhea following a suspected foodborne illness. She tested positive for COVID-19, human parainfluenza virus type 4, and enterovirus/rhinovirus in the hospital. She subsequently developed hypoxia, hypotension, and sepsis. Blood work revealed leukocytosis and elevated inflammatory markers. Imaging of her abdomen showed fluid-filled bowel loops suggesting acute gastroenteritis and colitis of infectious or inflammatory etiology. She was initially treated with antibiotics for a suspected bacterial infection. However, her cultures resulted negative and her symptoms slowly improved with supportive care including probiotics and a low-fat diet. Due to her persistent shortness of breath related to her COVID-19 infection, she was started on a course of oral prednisone due to the anti-inflammatory effects of steroids. She was discharged home in stable condition with close outpatient follow-up. This study highlights the clinical challenges of managing multiple viral infections, particularly with concurrent COVID-19.

摘要

我们报告了一例34岁女性病例,该患者因疑似食源性疾病出现发热、恶心、呕吐和腹泻后前往急诊科就诊。她在医院检测出新型冠状病毒肺炎(COVID-19)、4型人副流感病毒和肠道病毒/鼻病毒呈阳性。随后,她出现了缺氧、低血压和脓毒症。血液检查显示白细胞增多和炎症标志物升高。她腹部的影像学检查显示肠袢积液,提示为感染性或炎症性病因的急性肠胃炎和结肠炎。她最初因疑似细菌感染接受抗生素治疗。然而,她的培养结果为阴性,通过包括益生菌和低脂饮食在内的支持性治疗,她的症状逐渐改善。由于她因COVID-19感染而持续呼吸急促,鉴于类固醇的抗炎作用,她开始接受口服泼尼松治疗。她出院时病情稳定,门诊密切随访。本研究强调了管理多种病毒感染,尤其是合并COVID-19时的临床挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e6/11615252/b9bac9549f89/cureus-0016-00000072949-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e6/11615252/105479bd5ac8/cureus-0016-00000072949-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e6/11615252/b9bac9549f89/cureus-0016-00000072949-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e6/11615252/105479bd5ac8/cureus-0016-00000072949-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47e6/11615252/b9bac9549f89/cureus-0016-00000072949-i02.jpg

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