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普通病房和重症监护病房中新冠病毒肺炎住院患者的分析:来自拉丁美洲各中心RIMAC心肺影像登记处的见解

Analysis of COVID-19 patients hospitalized in general wards and intensive care units: Insights from the RIMAC cardiopulmonary imaging registry across Latin American centers.

作者信息

Reyes Graciela, Baltodano Roberto, D'Imperio Heraldo, Morales Cecilia, Moscoso Josh, Cupe-Chacalcaj Kelly, Cachicatari-Beltran Angela, Lopez Rosa, Velazco Ma Paula, Campos-Vieira Marcelo L, Hernández José M, Pignatelli Ricardo, Spina Salvador V

机构信息

Department of Cardiology, Hospital de Alta Complejidad en Red El Cruce. Florencio Varela, Provincia de Buenos Aires, Argentina.

Department of Cardiology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru.

出版信息

Arch Cardiol Mex. 2024 Dec 6;95(2):163-70. doi: 10.24875/ACM.24000068.

Abstract

OBJECTIVES

This study aimed to compare various aspects among coronavirus disease 2019 (COVID-19) patients admitted to general wards versus intensive care units (ICUs) in Latin American (LATAM), including demographics, comorbidities, imaging and laboratory findings, complications, treatments, and predictors of mortality.

MATERIALS AND METHODS

Data from the LATAM cardiopulmonary imaging registry of hospitalized COVID-19 patients (RIMAC) were analyzed. RIMAC is a prospective observational study conducted from March to December 2020 across 12 tertiary centers in nine LATAM countries.

RESULTS

Out of 1,435 patients, 49.34% were admitted to general wards and 50.66% to ICUs. Significant differences were observed between the two groups. ICU patients had a higher incidence of comorbidities, elevated biomarker levels, and complications such as kidney and heart failure, and required more intensive treatments. They also showed more severe imaging findings and had longer hospital stays with higher mortality rates compared to ward patients.

CONCLUSION

The study highlighted significant disparities between COVID-19 patients admitted to general wards and ICUs in LATAM. These disparities encompassed clinical severity, resource utilization, and mortality rates. Older age, obesity, extensive lung infiltrates, and kidney failure emerged as predictors of mortality. These findings underscore the need for tailored management strategies based on the severity of illness among COVID-19 patients in LATAM.

摘要

目的

本研究旨在比较拉丁美洲(LATAM)普通病房与重症监护病房(ICU)收治的2019冠状病毒病(COVID-19)患者在各个方面的情况,包括人口统计学特征、合并症、影像学和实验室检查结果、并发症、治疗方法以及死亡预测因素。

材料与方法

分析了LATAM住院COVID-19患者心肺成像登记处(RIMAC)的数据。RIMAC是一项前瞻性观察性研究,于2020年3月至12月在LATAM九个国家的12个三级中心进行。

结果

在1435例患者中,49.34%入住普通病房,50.66%入住ICU。两组之间观察到显著差异。ICU患者合并症发生率更高,生物标志物水平升高,且出现肾脏和心力衰竭等并发症,需要更强化的治疗。与病房患者相比,他们的影像学表现也更严重,住院时间更长,死亡率更高。

结论

该研究突出了LATAM普通病房和ICU收治的COVID-19患者之间的显著差异。这些差异包括临床严重程度、资源利用和死亡率。年龄较大、肥胖、广泛的肺部浸润和肾衰竭是死亡的预测因素。这些发现强调了在LATAM需要根据COVID-19患者的病情严重程度制定个性化管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/679e/12058105/761edd8b0053/10971AMEX252-ACM-95-163-g001.jpg

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