利用空间多组学揭示胚胎发育中的组织结构。
Leveraging spatial multiomics to unravel tissue architecture in embryo development.
作者信息
Jiang Fuqing, Wang Haoxian, Li Zhuxia, Cui Guizhong, Peng Guangdun
机构信息
Center for Cell Lineage Technology and Bioengineering, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, China-New Zealand Belt and Road Joint Laboratory on Biomedicine and Health, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Guangzhou Laboratory, Guangzhou, China.
出版信息
Trends Genet. 2025 Apr;41(4):271-274. doi: 10.1016/j.tig.2024.11.007. Epub 2024 Dec 7.
Spatial multiomics technologies have revolutionized biomedical research by enabling the simultaneous measurement of multiple omics modalities within intact tissue sections. This approach facilitates the reconstruction of 3D molecular architectures, providing unprecedented insights into complex cellular interactions and the intricate organization of biological systems, such as those underlying embryonic development.
空间多组学技术通过能够在完整组织切片内同时测量多种组学模态，彻底改变了生物医学研究。这种方法有助于三维分子结构的重建，为复杂的细胞相互作用以及生物系统的复杂组织（如胚胎发育的基础组织）提供了前所未有的见解。
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