Brooks R F, Shields R
Exp Cell Res. 1985 Jan;156(1):1-6. doi: 10.1016/0014-4827(85)90255-1.
By separating large and small 3T3 cells we show here that cell growth (in volume) after stimulation from quiescence is not 'autocatalytic'. Rather, large cells grow significantly more slowly, in relative terms, than small cells. It follows that 3T3 cells do not require a size control mechanism operating at the level of division timing in order to achieve cell size homeostasis.
通过分离大、小3T3细胞，我们在此表明，从静止状态受到刺激后的细胞生长（在体积方面）并非“自动催化”。相反，相对而言，大细胞的生长速度明显比小细胞慢。由此可见，3T3细胞为了实现细胞大小的稳态，并不需要一种在分裂时间层面起作用的大小控制机制。
