Styslinger L, Kirksey A
Am J Clin Nutr. 1985 Jan;41(1):21-31. doi: 10.1093/ajcn/41.1.21.
Vitamin B-6 has been reported to vary in concentration in human milk in response to changes in maternal intake of the vitamin. This study examined the effects of such changes on the breastfed infants' intake of vitamin B-6. Lactating mothers received 0, 2.5, 10.0 or 20.0 mg pyridoxine X HCl (PN X HCl) for 3 consecutive days in addition to dietary sources. Dietary intakes of vitamin B-6 (mean = 1.8 +/- 0.2 mg/day) were similar among the four groups. Vitamin B-6 was determined in milk samples from each feeding and milk intakes of infants were estimated by test-weighing. Nonsupplemented mothers had lower vitamin B-6 in their milk (93 +/- 8 micrograms/L) and vitamin B-6 intake of their infants was lower (0.06 +/- 0.01 mg/day) compared to other groups. Maternal supplementation with 2.5, 10.0 or 20.0 mg PN X HCl was paralleled by vitamin B-6 levels in milk of 192 +/- 16, 247 +/- 25 and 413 +/- 45 micrograms/L, respectively, and by vitamin B-6 intakes of breastfed infants of 0.12 +/- 0.02, 0.22 +/- 0.02 and 0.28 +/- 0.03 mg/day, respectively. When maternal intakes of vitamin B-6 approximated 20.0 mg/day, breastfed infants were unlikely to receive the current RDA of 0.3 mg vitamin B-6/day.
据报道，母乳中维生素B-6的浓度会随着母亲维生素摄入量的变化而改变。本研究调查了这种变化对母乳喂养婴儿维生素B-6摄入量的影响。哺乳期母亲除了从饮食中获取维生素外，连续3天分别摄入0、2.5、10.0或20.0毫克盐酸吡哆醇（PN·HCl）。四组母亲的维生素B-6饮食摄入量（平均 = 1.8±0.2毫克/天）相似。测定每次喂奶母乳样本中的维生素B-6含量，并通过称重估算婴儿的母乳摄入量。与其他组相比，未补充维生素的母亲母乳中维生素B-6含量较低（93±8微克/升），其婴儿的维生素B-6摄入量也较低（0.06±0.01毫克/天）。母亲补充2.5、10.0或20.0毫克PN·HCl后，母乳中维生素B-6水平分别为192±16、247±25和413±45微克/升，母乳喂养婴儿的维生素B-6摄入量分别为0.12±0.02、0.22±0.02和0.28±0.03毫克/天。当母亲维生素B-6摄入量接近20.0毫克/天时，母乳喂养的婴儿不太可能达到目前每天0.3毫克维生素B-6的推荐膳食摄入量。
