Liu Yingying, Jiang Hui, Nie Zizheng, Yu Bin, Qiu Xinyi, Zuo Hui, Han Shufen
School of Public Health, Hangzhou Normal University, Hangzhou, Zhejiang, China.
School of Public Health, Soochow University Medical College, Suzhou, Jiangsu, China.
Front Public Health. 2024 Nov 27;12:1493580. doi: 10.3389/fpubh.2024.1493580. eCollection 2024.
Maternal moderate-intensity exercise during pregnancy has important health benefits for the offspring, however, less is known about its association with offspring attention-deficit/hyperactivity disorder (ADHD). This study aimed to explore the association between maternal exercise during pregnancy and ADHD among preschool children in Southwest China.
A web-based cross-sectional study was performed in 2021, and the revised Conners Parental Symptom Questionnaire and maternal exercise during pregnancy were obtained through a self-reported structured questionnaire. A binary logistic regression model was used to assess the association between maternal exercise during pregnancy and the likelihood of childhood ADHD after adjustment for covariates.
A total of 4,184 preschool children aged 3-6 years were included in our final analysis. Children whose mothers exercised for <20 min per day were more likely to be at risk of ADHD (6.3%), compared to those whose mothers exercised for more than 40 min (3.1%) or 20-40 min (2.8%) per day. Daily exercise of <20 min during pregnancy was associated with higher odds of childhood ADHD (adjusted OR = 2.11; 95% CI: 1.41, 3.16) after multivariable adjustment. The association of maternal exercise during pregnancy with childhood ADHD was similar in subgroups stratified by child's sex, and by maternal smoking, sleep duration and gestational anemia during pregnancy.
Our findings highlight the importance of maternal moderate-intensity exercise during pregnancy for the prevention of childhood ADHD. Prospective studies are needed to confirm our findings in the future.
孕期母亲进行中等强度运动对后代有重要的健康益处，然而，关于其与后代注意力缺陷多动障碍（ADHD）的关联知之甚少。本研究旨在探讨中国西南部地区孕期母亲运动与学龄前儿童ADHD之间的关联。
2021年开展了一项基于网络的横断面研究，通过自填式结构化问卷获取修订版的康纳斯父母症状问卷以及孕期母亲运动情况。采用二元逻辑回归模型评估孕期母亲运动与调整协变量后儿童患ADHD可能性之间的关联。
最终分析纳入了4184名3至6岁的学龄前儿童。与母亲每天运动超过40分钟（3.1%）或20至40分钟（2.8%）的儿童相比，母亲每天运动少于20分钟的儿童患ADHD的风险更高（6.3%）。多变量调整后，孕期每天运动少于20分钟与儿童患ADHD的较高几率相关（调整后的比值比=2.11；95%置信区间：1.41，3.16）。孕期母亲运动与儿童ADHD之间的关联在按儿童性别、母亲孕期吸烟、睡眠时间和孕期贫血分层的亚组中相似。
我们的研究结果凸显了孕期母亲进行中等强度运动对预防儿童ADHD的重要性。未来需要进行前瞻性研究来证实我们的发现。
