Jung Il Gu, Jung Hahn Jin, Shim Woo Sub
Department of Otorhinolaryngology-Head and Neck Surgery, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Republic of Korea.
J Rhinol. 2022 Jul;29(2):118-121. doi: 10.18787/jr.2022.00404. Epub 2022 Jul 27.
Herpes zoster ophthalmicus (HZO) occurs due to reactivation of dormant varicella zoster virus infection in the ophthalmic division of the trigeminal nerve. Hutchinson's sign, a herpetic skin lesion in the nasal tip, is a predictor of ocular complications, as the nasal tip area and ocular structure are innervated by the same nasociliary nerve. Patients who present with Hutchinson's sign should be referred to an ophthalmologist due to possibility of ocular complications. Here, we present a case of a 44-year-old man with HZO that was confused with delayed rhinoplasty complication. The patient presented with nasal tip skin lesions 17 years after undergoing augmentation rhinoplasty. A graft-related infection was suspected due to operation history and skin lesions. However, surgical exploration disclosed no infection or inflammation, and serological tests revealed positive varicella zoster virus immunoglobulin M, and immunoglobulin G, antibodies. Based on these findings, the patient was diagnosed with HZO. Further, the patient received antiviral treatment with famciclovir. The lesions gradually improved with conservative treatment and became almost unrecognizable. Therefore, HZO should be considered when there is an unexplained skin lesion at the nasal tip in patients with history of rhinoplasty.
眼部带状疱疹(HZO)是由于潜伏在三叉神经眼支的水痘-带状疱疹病毒感染重新激活所致。哈钦森征(鼻尖部的疱疹性皮肤损害)是眼部并发症的一个预测指标,因为鼻尖区域和眼部结构由同一鼻睫神经支配。出现哈钦森征的患者因有发生眼部并发症的可能,应转诊给眼科医生。在此,我们报告一例44岁患有HZO的男性患者,其病情曾被误诊为延迟性隆鼻并发症。该患者在隆鼻术后17年出现鼻尖皮肤损害。由于手术史和皮肤损害,怀疑有移植物相关感染。然而,手术探查未发现感染或炎症,血清学检测显示水痘-带状疱疹病毒免疫球蛋白M和免疫球蛋白G抗体呈阳性。基于这些发现,该患者被诊断为HZO。此外,患者接受了泛昔洛韦抗病毒治疗。经保守治疗,皮损逐渐改善,几乎难以辨认。因此,有隆鼻史的患者鼻尖出现不明原因皮肤损害时,应考虑眼部带状疱疹。